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structure nameCRYSTAL STRUCTURE OF DNMT3B-DNMT3L IN COMPLEX WITH CPGPA DNA
(DNA CYTOSINE-5-METHYLTRANSFERASE 3B)
referenceSong et al. 'Nat 11 3355 2020
sourceHOMO SAPIENS
experimentX-ray (resolution=3.05, R-factor=0.209)
structural superfamilyS-adenosyl-L-methionine-dependent methyltransferases;
sequence familyC5 cytosinespecific DNA methylase 740;
multimeric complexes6kda_AD 6kdb_AD 6u8p_AD 6u8v_AD 6u8w_AD 6u8x_AD 6u90_AD 6u91_AD
reference complex6kdb_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNVNPTKSN

Estimated binding specificities ?

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# IC=2.574 IC/col=0.644 n_of_columns=4 specificity:   
A |  10   0  81  19
C |  10   0   7  16
G |  63  96   4  16
T |  13   0   4  45
scan!

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updated Fri Jan 9 10:21:20 2026