interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF DNMT3B-DNMT3L IN COMPLEX WITH CPGPA DNA
(DNA CYTOSINE-5-METHYLTRANSFERASE 3B)
referenceSong et al. 'Nat 11 3355 2020
sourceHOMO SAPIENS
experimentX-ray (resolution=3.05, R-factor=0.209)
structural superfamilyS-adenosyl-L-methionine-dependent methyltransferases;
sequence familyC5 cytosinespecific DNA methylase 740;
multimeric complexes6kda_AD 6kdb_AD 6u8p_AD 6u8v_AD 6u8w_AD 6u8x_AD 6u90_AD 6u91_AD
reference complex6kdb_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNVNPTKSN

Estimated binding specificities ?

readout + contactlogo
# IC=2.687 IC/col=0.672 n_of_columns=4 specificity:   
A |  48   4   0  10
C |  16   4  96  63
G |  16   4   0  13
T |  16  84   0  10
scan!

home
updated Mon Dec 18 18:21:03 2023