interface graph thumbnail
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structure nameCRYSTAL STRUCTURE OF DNMT3B(K777A)-DNMT3L IN COMPLEX WITH CPGPT DNA
referenceZhang et al. 'Nat 11 3355 2020
experimentX-ray (resolution=2.95, R-factor=0.217)
structural superfamilyS-adenosyl-L-methionine-dependent methyltransferases;
sequence familyC5 cytosinespecific DNA methylase 737;
multimeric complexes6kda_AD 6kdb_AD 6u8p_AD 6u8v_AD 6u8w_AD 6u8x_AD 6u90_AD 6u91_AD
reference complex6kdb_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNVPTASN

Estimated binding specificities ?

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# IC=3.070 IC/col=0.614 n_of_columns=5 specificity:   
A |  10   5   0  10  10
C |  10   0   0  15  15
G |  11  90  96  30  36
T |  65   1   0  41  35
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updated Fri Jan 9 10:22:05 2026