3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.

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updated Tue Jan 6 18:34:13 2026

structure name	STRUCTURE OF HUMAN CGAS (K394E) BOUND TO THE NUCLEOSOME
source	HOMO SAPIENS
experiment	NMR
structural superfamily	Histone-fold;PH domain-like;lambda repressor-like DNA-binding domains;p53-like transcription factors;
reference complex	5o9g_F 6a5l_g 6buz_H 6fq8_A 6r8y_H 6see_H 6t7a_H 6upk_H 6x0n_f 6x59_H 6y5d_H 7ccr_H 7e8d_H 7jzv_N 7k5x_H 7k60_H 7k63_H 7lyb_G 7nkx_f 7pet_H 7u0g_M 7vdt_B 7xzx_N 8txv_G 8u14_G 8upf_G
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 6y5d_A interface=3,4, phRYrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlrfqssavmalqeaseaylvglfedtnlaaihakrvtimpkdiqlarrirge > 6y5d_B interface= lrDNiqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 6y5d_C interface=1,32, RakaksrssraglqfpvgrvhrllrkgnyaeRvgagapvymaavleyltaeilelagnaardnkktriiprhlqlairndeelnkllgkvtiaqggvlpniqavllp > 6y5d_D interface=2, sRkesysvyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsa > 6y5d_E interface=2,3,4,46, pHRYrpgtvalreirryqkstellirklpfqrlvreiaqdfktdlRfqssavmalqeaseaylvglfedtnlaaihakrvtimpkdiqlarrirge > 6y5d_F interface= kVLRdniqgitkpairrlarrggvkrisgliyeetrgvlkvflenVirdavtytehakrktvtamdvvyalkrqgrtlygfgg > 6y5d_G interface=1, Rakaksrssraglqfpvgrvhrllrkgnyaervgagapvymaavleyltaeilelagnaardnkktriiprhlqlairndeelnkllgkvtiaqggvlpniqavllpk > 6y5d_H interface=3, rsRkesysvyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavtkytsa