3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameNUCLEOSOME FROM A DIMERIC PRC2 BOUND TO A NUCLEOSOME
(HISTONE H3)
sourceXENOPUS LAEVIS
experimentNMR
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes6r1t_ABCDEFGH 7ktq_ABCDEFGH 7xd0_ABCDEFGHKL
redundant complexes6r1t 7xd0
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  RG--RT----       +-----------------------------8grq_A    
                   !  
  RG--------       !                            +8jh2_e    
                   !      +---------------------4 
  RGLCRT----     -11      !                     +8hr1_E    
                   !      !  
  ----RA----       !      !                   +--7xsx_a    
                   !      !           +-------5 
  ------RA--       !      !           !       +--6g0l_D    
                   +-----10     +-----6 
  ----RA----              !     !     !          +1zla_C    
                          !     !     +----------2 
  ----RG----              !  +--8                +8ox0_C    
                          !  !  ! 
  ----RG----              !  !  !                +8txv_G    
                          !  !  ! +--------------1 
  ----RG----              +--9  +-7              +5x0y_G    
                             !    ! 
  ----RG----                 !    +--------------8jla_C    
                             ! 
  ----RT----                 !                  +8u14_G    
                             +------------------3 
  ----RA--RA                                    +6a5l_g    
                 

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updated Wed Dec 18 09:33:34 2024