7q3o_C : 3D-footprint complex

structure name	STRUCTURE OF CDX1 BOUND TO HYDROXYMETHYLATED DNA (Homeobox protein CDX-1)
reference	Morgunova et al. 'To ? ? ?
source	Homo sapiens
experiment	X-ray (resolution=2.78, R-factor=0.220)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
redundant complexes	5lux_K
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7q3o_C interface=7,8,49,50,53,54, trtkdkYRvvytdhqrlelekefhysryitirrkselaanlglterqvKIwfQNrrakerkvn
interface signature	YRKIQN

Estimated binding specificities ?

contact

# IC=6.271 IC/col=0.784 n_of_columns=8

specificity:

A |   0   0   0  96  16   8  24  16
C |   0   0   0   0   8   8  24  48
G |   0   0   0   0  16  72  24  16
T |  96  96  96   0  56   8  24  16

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RT--QTVAQTNA------   L                               +8osb_E    
                                                +------1 
  RT----VTKGNA--KA--   L                        !      +2lkx_A    
                                           +----5 
  ------NCICRG------   L                   !    !        +4xrm_B    
                                           !    !      +-2 
  ------NCITNARGRG--   L                   !    +------3 +6fqq_E    
                             +-------------6           ! 
  --RT--NT--NAIARG--   L     !             !           +4cyc_B    
                             !             ! 
  RT----IAQCNAMG----   L   +-7             !      +----1b72_A    
                           ! !             +------4 
  RC----IAQCNAYC----   L   ! !                    +----3rkq_B    
                         --8 ! 
  ------VTCCNAQA--RT   L   ! +-------------------------8g87_X    
                           ! 
  ------------YCFAKC   L   +--------------------------6pe2_B

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updated Tue Jun 30 07:48:36 2026