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legend  pdf

structure nameCRYSTAL STRUCTURE OF S. AUREUS MEPR-DNA COMPLEX
(MEPR)
referenceBrennan et al. 'Nucleic 42 2774 2014
sourceSTAPHYLOCOCCUS AUREUS
experimentX-ray (resolution=2.84, R-factor=0.208)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyMarR family;
multimeric complexes4lll_AB 4lll_CD 4lll_IJ 4lln_AB 4lln_CD 4lln_IJ
redundant complexes4lll_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTPTSNR

Estimated binding specificities ?

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# IC=6.292 IC/col=0.699 n_of_columns=9 specificity:   
A |   0   9   0  75  73  24  24  73  96
C |   0  73   0   7   7  24  24   7   0
G |   0   7   0   7   9  24  24   9   0
T |  96   7  96   7   7  24  24   7   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: MEPR
GTTAGPubMed4lln_I(2.93e-03), 4lln_CD(1.29e-02), 4lll_D(2.95e-03)
GTTAGATPubMed4lln_I(3.84e-04), 4lll_AB(6.35e-03), 4lll_CD(6.40e-03), ... (total=8)

Dendrogram of similar interfaces ?

matrix format
  
  --DCLT--AGTTRG----RG----RA----   L                                     +5h3r_A    
                                                         +---------------1 
  ------------RC--YG----KT------                   +-----2               +2acj_B    
                                                   !     ! 
  ----RGSTRTSTHG----------RA----   L       +-------3     +---------------3zpl_B    
                                           !       ! 
  TT----KATTQTTG--LTRTKA----FTYT   L     +-4       +---------------------2p7c_B    
                                         ! ! 
  ----RGTCTA--RGNT--------RT----   L   +-5 +-----------------------------4fx4_B    
                                       ! ! 
  ----------------YG------------     --6 +-----------------------------3eyi_B    
                                       ! 
  --ITRGECSCSGKG----------------   L   +-----------------------------5i2d_R    
                                     

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updated Sat Jan 10 07:13:55 2026