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legend  pdf

structure nameCRYSTAL STRUCTURE OF S. AUREUS MEPR-DNA COMPLEX
(MEPR)
referenceBrennan et al. 'Nucleic 42 2774 2014
sourceSTAPHYLOCOCCUS AUREUS
experimentX-ray (resolution=2.84, R-factor=0.208)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyMarR family;
multimeric complexes4lll_AB 4lll_CD 4lll_IJ 4lln_AB 4lln_CD 4lln_IJ
redundant complexes4lll_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTPTSNR

Estimated binding specificities ?

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# IC=6.292 IC/col=0.699 n_of_columns=9 specificity:   
A |   0   9   0  73  75  24  24  73  96
C |   0  73   0   7   7  24  24   7   0
G |   0   7   0   7   7  24  24   9   0
T |  96   7  96   9   7  24  24   7   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: MEPR
GTTAGPubMed4lln_I(2.93e-03), 4lln_CD(1.29e-02), 4lll_D(2.95e-03)
GTTAGATPubMed4lln_I(3.84e-04), 4lll_AB(6.35e-03), 4lll_CD(6.40e-03), ... (total=8)

Dendrogram of similar interfaces ?

matrix format
  
  --DCLT--AGTTRG----RG--RA----   L         +-----------------------------5h3r_A    
                                         +-2 
  ----RGSTRTSTHG--------RA----   L       ! !          +------------------3zpl_B    
                                       +-3 +----------1 
  --ITRGECSCSGKG--------------   L     ! !            +------------------5i2d_R    
                                     +-4 ! 
  TT----KATTQTTG--LTRTKA--FTYT   L   ! ! +-----------------------------2p7c_B    
                                   --5 ! 
  ----------------YG----------       ! +-----------------------------3eyi_B    
                                     ! 
  ----RGTCTA--RGNT------RT----   L   +-----------------------------4fx4_B    
                                   

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updated Fri Sep 13 18:28:21 2024