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structure nameGENERAL STRUCTURE-BASED APPROACH TO THE DESIGN OF PROTEIN LIGANDS: APPLICATION TO THE DESIGN OF KV1.2 POTASSIUM CHANNEL BLOCKERS.
(Z-DNA binding protein 1)
referenceCharbonnier et al. J.Am.Chem.Soc. 128 16190 2006
sourceMus musculus
experimentX-ray (resolution=1.70, R-factor=0.248)
structural superfamily"Winged helix" DNA-binding domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  ------------------------------YG----------                                                              +2heo_D    
                                                                                           +--------------1 
  ----------------NT--TCTA--------------RT--   L                                     +-----4              +5zux_A    
                                                                                     !     ! 
  ------LT------RTSGTG--QTRG----------------   L                                   +-5     +--------------2xro_E    
                                                                                   ! ! 
  --------SGQG--YCNC------------------------                                     +-6 +--------------------2ve9_C    
                                                                                 ! ! 
  --------------RCTT----TTHT--LA------------   L                               +-7 +----------------------7e1b_B    
                                                                               ! ! 
  ------------DCLT--AG--TTRG------RG------RA   L                             +-8 +------------------------5h3r_A    
                                                                             ! ! 
  ----------------TTHT----KG--------RC------   L                           +-9 +-------------------------7b0c_A    
                                                                           ! ! 
  RGRTKG----------------------------YG------   L                        +-10 +-------------------------6lui_A    
                                                                        !  !  
  --------------RC------RC------------------                         +-11  +--------------------------6wfq_C    
                                                                     !  !  
  --------TC--STKTPTTT--FT--------------RT--                      +-12  +--------------------------4ass_H    
                                                                  !  !  
  --------------MGSGTT--TTYC----------------   L               +-13  +---------------------------5f7q_C    
                                                               !  !  
  ----------------NTVC--ECSTYT--STYC--RA----   L            +-14  +---------------------------5ed4_A    
                                                            !  !  
  ------------------RG--YC------------------   L         +-15  +---------------------------1cf7_B    
                                                         !  !  
  ------------------SA----------------------          +-16  +---------------------------3l4j_A    
                                                      !  !  
  ------------SGRCRGTG--DCRG----------------   L      !  +----------------------------3w6v_A    
                                                   +-17  
  --------------------SA--------------------   L   !  !                           +5npk_d    
                                                   !  !                     +-----2 
  --------------------SA--------------------     -18  +---------------------3     +2xcr_U    
                                                   !                        ! 
  ----------------QAAG----------------------   L   !                        +------5zen_A    
                                                   !  
  ----------------SCTA--KTVCHT--KG----------   L   +----------------------------1je8_F    
                                                 

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updated Fri Sep 13 16:21:11 2024