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legend  pdf

structure nameCRYSTAL STRUCTURE OF GSX2 HOMEODOMAIN IN COMPLEX WITH DNA
(GS homeobox 2)
referenceKovall et al. 'To ? ? ?
sourceMus musculus
experimentX-ray (resolution=2.21, R-factor=0.225)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRIQN

Estimated binding specificities ?

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# IC=5.971 IC/col=0.853 n_of_columns=7 specificity:   
A |   0  48  24   0   0  96  64
C |   0  16  24   0   0   0  16
G |   0  16  24   0   0   0  16
T |  96  16  24  96  96   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RT--IAQCNAMG----   L                          +---1b72_A    
                                        +-------2 
  RTQTVAQTNA------   L                  !       !   +8osb_E    
                                   +----3       +---1 
  RT--VTKGNA--KA--   L             !    !           +2lkx_A    
                           +-------4    ! 
  ----NCICNARGRG--   L     !       !    +-----------4xrm_B    
                         +-5       ! 
  RC--IAQCNAYC----   L   ! !       +----------------3rkq_B    
                       --6 ! 
  ----VTCCNAQA--RT   L   ! +------------------------8g87_X    
                         ! 
  ----------YCFAKC   L   +-------------------------6pe2_B    
                       

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updated Sun Aug 3 23:59:47 2025