8eml_B : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF GSX2 HOMEODOMAIN IN COMPLEX WITH DNA (GS homeobox 2)
reference	Kovall et al. 'To ? ? ?
source	Mus musculus
experiment	X-ray (resolution=2.21, R-factor=0.225)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8eml_B interface=3,45,48,49, rmRtaftstqllelerefssnmylsrlrrieiatylnlsekqvkIwfQNrrvkhkke
interface signature	RIQN

Estimated binding specificities ?

readout + contact

# IC=5.245 IC/col=0.749 n_of_columns=7

specificity:

A |   2   0  74  96  10  24  85
C |  10   0  10   0  10  24   0
G |  10   0   2   0  12  24   1
T |  74  96  10   0  64  24  10

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RT--QTVAQTNA------   L                               +8osb_E    
                                                +------1 
  RT----VTKGNA--KA--   L                        !      +2lkx_A    
                                        +-------5 
  ------NCICNARGRG--   L                !       !        +4xrm_B    
                                        !       !      +-2 
  ------NCITNARGRG--   L                !       +------3 +6fqq_E    
                             +----------6              ! 
  --RT--NT--NAIARG--   L     !          !              +4cyc_B    
                             !          ! 
  RT----IAQCNAMG----   L   +-7          !         +----1b72_A    
                           ! !          +---------4 
  RC----IAQCNAYC----   L   ! !                    +----3rkq_B    
                         --8 ! 
  ------VTCCNAQA--RT   L   ! +-------------------------8g87_X    
                           ! 
  ------------YCFAKC   L   +--------------------------6pe2_B

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updated Tue Jun 30 15:10:19 2026