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legend  pdf

structure nameCRYSTAL STRUCTURE OF GSX2 HOMEODOMAIN IN COMPLEX WITH DNA
(GS homeobox 2)
referenceKovall et al. 'To ? ? ?
sourceMus musculus
experimentX-ray (resolution=2.21, R-factor=0.225)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRIQN

Estimated binding specificities ?

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# IC=5.971 IC/col=0.853 n_of_columns=7 specificity:   
A |   0  48  24   0   0  96  64
C |   0  16  24   0   0   0  16
G |   0  16  24   0   0   0  16
T |  96  16  24  96  96   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RTQTVAQTNA------   L                              +8osb_E    
                                                  +-1 
  RT--VTKGNA--KA--   L                  +---------2 +2lkx_A    
                                        !         ! 
  RT--IAQCNAMG----   L             +----3         +-1b72_A    
                                   !    ! 
  ----NCICNARGRG--   L     +-------4    +-----------4xrm_B    
                           !       ! 
  RC--IAQCNAYC----   L   +-5       +----------------3rkq_B    
                         ! ! 
  ----VTCCNAQA--RT   L --6 +------------------------8g87_X    
                         ! 
  ----------YCFAKC       +-------------------------6pe2_B    
                       

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updated Sat Sep 14 09:53:18 2024