8hcl_A : 3D-footprint complex

structure name	ZEBRAFISH IRF-10 DBD COMPLEX WITH DNA (Interferon regulatory factor 10)
reference	Ouyang et al. 'J ? ? 2024
source	Danio rerio
experiment	X-ray (resolution=1.99, R-factor=0.225)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Interferon regulatory factor transcription f;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8hcl_A interface=35,74,77,78,79,82, mrlrewliaqidsaeypglswenaeksmfripwkHaakqdyrqnqdaalfkawamykgkfqegrdkadpstwkTrlRCAlnKstdfqevsersqldisepykvyriled
interface signature	HTRCAK

Estimated binding specificities ?

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# IC=4.600 IC/col=0.767 n_of_columns=6

specificity:

A |   5  11   0   5   0  70
C |  80  10   0  16  96  16
G |  11  10   0  40   0   5
T |   0  65  96  35   0   5

scan!

Dendrogram of similar interfaces ?

matrix format

  
  HTLT----RGNTRGSTAT--RA--   L       +-----------------------------2o6g_G    
                                   +-3 
  ----QCKTRGAT--RGNT------   L     ! +-----------------------------8smh_F    
                                 +-4 
  ----DCKTRG----RGYA----KA   L   ! !                            +5jvt_A    
                                 ! +----------------------------2 
  ----DCKTRGST--RGYA------   L --5                              +4bnc_A    
                                 ! 
  ----------STRTHT--ST----   L   !                             +3l2c_A    
                                 +-----------------------------1 
  ----------STRTHT--STLT--   L                                 +4lg0_A

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updated Sun Jan 11 00:09:36 2026