interface graph thumbnail
legend  pdf

structure nameZEBRAFISH IRF-10 DBD COMPLEX WITH DNA
(Interferon regulatory factor 10)
referenceOuyang et al. 'J ? ? 2024
sourceDanio rerio
experimentX-ray (resolution=1.99, R-factor=0.225)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyInterferon regulatory factor transcription f;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHTRCAK

Estimated binding specificities ?

readout + contactlogo
# IC=5.055 IC/col=0.842 n_of_columns=6 specificity:   
A |   6   1   9  96  78   6
C |   6   0   6   0   6   6
G |   6  89  75   0   6  78
T |  78   6   6   0   6   6
scan!

Dendrogram of similar interfaces ?

matrix format
  
  HTLT------RGNT--RGSTAT--RA--   L             +-----------------------------2o6g_G    
                                             +-1 
  ----QCKT--RGAT----RGNT------   L         +-2 +-----------------------------8smh_F    
                                           ! ! 
  ----DCKT--RG------RGYA----KA   L       +-3 +-----------------------------5jvt_A    
                                         ! ! 
  ------ECKT--RGAT--RG--------   L     +-4 +-----------------------------1pue_E    
                                       ! ! 
  ----DCKT--RGST----RGYA------   L   +-5 +-----------------------------4bnc_A    
                                     ! ! 
  ------------ST--RTHT--STLT--   L --6 +-----------------------------4lg0_A    
                                     ! 
  ------------ST--RTHT--ST----   L   +-----------------------------3l2c_A    
                                   

home
updated Tue Jun 30 16:32:32 2026