interface graph thumbnail
legend  pdf

structure nameAML1/CBF-BETA/DNA COMPLEX
(CORE-BINDING FACTOR ALPHA SUBUNIT1)
referenceWarren et al. Nat.Struct.Biol. 8 371 2001
sourceHOMO SAPIENS
experimentX-ray (resolution=2.60, R-factor=0.237)
structural superfamilyp53-like transcription factors;
sequence familyRunt domain;
redundant complexes1hjc 1io4 1hjb
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRVDRR

Estimated binding specificities ?

contactlogo
# IC=6.280 IC/col=0.897 n_of_columns=7 specificity:   
A |   0   0   0   0  14  27  12
C |   0  96   0   0  25  19   0
G |  96   0  96  96   6  12  72
T |   0   0   0   0  51  38  12
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: AML-1
TGTGGTPubMed1hjb_ABC(3.30e-07), 1hjb_DEF(3.42e-07), 1io4_ABC(3.57e-07), ... (total=5)

home
updated Mon Dec 16 17:53:07 2024