interface graph thumbnail
legend  pdf

structure nameAML1/CBF-BETA/DNA COMPLEX
(CORE-BINDING FACTOR ALPHA SUBUNIT1)
referenceWarren et al. Nat.Struct.Biol. 8 371 2001
sourceHOMO SAPIENS
experimentX-ray (resolution=2.60, R-factor=0.237)
structural superfamilyp53-like transcription factors;
sequence familyRunt domain;
multimeric complexes3wu1_AB 4l18_AB 4l18_EF
redundant complexes1hjc 1io4 1hjb
reference complex4l18_E
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRVDRR

Estimated binding specificities ?

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# IC=6.249 IC/col=0.893 n_of_columns=7 specificity:   
A |  16  56  56   0   0   0   0
C |  64  16   8  96  96   0  96
G |   8  16  16   0   0  96   0
T |   8   8  16   0   0   0   0
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Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: AML-1
TGTGGTPubMed1hjb_ABC(3.30e-07), 1hjb_DEF(3.42e-07), 1io4_ABC(3.57e-07), ... (total=5)

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updated Thu Sep 12 14:42:40 2024