1puf_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF HOXA9 AND PBX1 HOMEODOMAINS BOUND TO DNA (HOMEOBOX PROTEIN HOX-A9)
reference	Laronde-Leblanc et al. 'Genes 17 2060 2003
source	MUS MUSCULUS
experiment	X-ray (resolution=1.90, R-factor=0.233)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
multimeric complexes	1puf_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1puf_A interface=14,17,59,62,63,66, nnpaanwlharstRkkRcpytkhqtlelekeflfnmyltrdrryevarllnlterqvkIwfQNrrMkmkkinkdrak
interface signature	RRIQNM

Estimated binding specificities ?

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# IC=5.300 IC/col=0.757 n_of_columns=7

specificity:

A |  11   0  96   0  24  67  11
C |   9   0   0  96  24   9  67
G |   9   0   0   0  24   9   9
T |  67  96   0   0  24  11   9

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RART--VTKGNA--KA--   L   +-----------------------------2lkx_A    
                           ! 
  --RT--IAQCNAMG----   L   !                        +----1b72_A    
                         --5                +-------2 
  --RTQTVAQTNA------   L   !                !       !   +8osb_E    
                           !     +----------3       +---1 
  ------NCICNARGRG--   L   !     !          !           +4xrm_B    
                           +-----4          ! 
  --RC--IAQCNAYC----   L         !          +------------3rkq_B    
                                 ! 
  ------VTCCNAQA--RT   L         +-----------------------8g87_X

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updated Sun Aug 3 05:51:42 2025