| structure name | CRYSTAL STRUCTURE OF HOXA9 AND PBX1 HOMEODOMAINS BOUND TO DNA (PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR-1) |
| reference | Laronde-Leblanc et al. 'Genes 17 2060 2003 |
| source | HOMO SAPIENS |
| experiment | X-ray (resolution=1.90, R-factor=0.233) |
| structural superfamily | Homeodomain-like; |
| sequence family | Homeobox domain; |
| multimeric complexes | 1b72_AB 1puf_AB |
| redundant complexes |  1lfu_P
1b72
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | RNNIR |
Estimated binding specificities ?
| readout + contact |  |
A | 17 61 0 0 96 11 C | 8 8 0 96 0 8 G | 10 19 0 0 0 8 T | 61 8 96 0 0 69scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: PBX1 | ||
| ATCAATCAA | PubMed | 1puf_B(1.14e-02), 1puf_AB(1.49e-03) |
| TGATTGAC | PubMed | 1puf_B(7.15e-03), 1puf_AB(7.14e-07) |
| TGATTGAT | PubMed | 1puf_B(7.15e-03), 1puf_AB(3.42e-04) |
| TTGAT | PubMed | 1puf_B(4.18e-04), 1puf_AB(7.82e-03) |
| TGATTAAT | PubMed | 1puf_B(7.15e-03), 1puf_AB(3.42e-04) |
| TTGATTGAT | PubMed | 1puf_B(1.14e-02), 1puf_AB(1.49e-03) |
| ATCAATCA | PubMed | 1puf_B(7.15e-03), 1puf_AB(3.42e-04) |
Dendrogram of similar interfaces ?
matrix format--------NCITNA------RGRG L +6fqq_E +-----------------------------1 ----RT--NT--NAIARG------ L +-3 +4cyc_B ! ! RART----VTKGNAKA-------- L +-4 +-----------------------------2lkx_A ! ! --RC----IAQCNAYC-------- L +-5 +-----------------------------3rkq_B ! ! --------NCICNA----RGRG-- L --6 +-----------------------------4xrm_B ! --RT--QTVAQTNA---------- L ! +8osb_E +----------------------------2 --RT----IAQCNAMG-------- L +1b72_A |
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updated Mon Jun 29 14:35:55 2026