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structure nameSTRUCTURAL BASIS OF HETERODIMERIC ECDYSTEROID RECEPTOR INTERACTION WITH NATURAL RESPONSE ELEMENT HSP27 GENE PROMOTER
(ECDYSONE RECEPTOR)
referenceKolodziejczyk et al. 'Nucleic 35 2705 2007
sourceDROSOPHILA MELANOGASTER
experimentX-ray (resolution=1.95, R-factor=0.182)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyZinc finger, C4 type two domains;
multimeric complexes1r0n_AB 1r0o_AB 2han_AB
redundant complexes1r0o_B 1r0n
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: ECDYSTEROID RECEPTOR
AGGTCAPubMed1r0n_AB(1.09e-04), 1r0o_AB(6.75e-05), 1r0o_B(1.24e-07), ... (total=4)
GGTTCAATGCACTPubMed2han_B(8.75e-03), 1r0n_AB(1.01e-03), 1r0o_AB(5.41e-03), ... (total=4)

Dendrogram of similar interfaces ?

matrix format
  
  --EA--KG--RTRTRT----                         +2han_B    
                                            +--1 
  --EA--KG--RTRTRT----       +--------------9  +4umm_E    
                             !              ! 
  --EC--KA--RGRG------   L   !              +--4nqa_I    
                             !  
  --EC--KG--RGRG----KA   L   !            +----2nll_B    
                             !            !  
  HGECAGKGAAKGRT------   L   !         +-10    +1lo1_A    
                             !         !  !  +-2 
  --EC--KG--KGRG--RC--   L   !         !  +--8 +2ff0_A    
                           -15         !     ! 
  ------KGVT--RG------   L   !  +-----12     +-5cbz_E    
                             !  !      !  
  --EA--KG--KTRG------   L   !  !      !        +2han_A    
                             !  !      !      +-3 
  --EC--KG--KGRG------       !  !      +------5 +3dzy_A    
                             !  !             ! 
  --DG--KG--RTRG------   L   !  !             +3cbb_A    
                             +-14  
  ------KGVT--RG------          !              +-1r4i_A    
                                !          +---7 
  --ET--KGAT--RG------   L      !          !   ! +1lat_A    
                                !          !   +-6 
  --EC--KG--RGRG------   L      !  +------11     +3dzy_D    
                                !  !       !  
  --EC--KG--KGRG------   L      !  !       !     +1ynw_B    
                                +-13       +-----4 
  --EC--KG--RGRG------   L         !             +5uan_B    
                                   !  
  --EC--KG--KTRG------   L         +-------------2nll_A    
                           

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updated Tue Dec 17 22:47:09 2024