interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE COMPLEX COMPRISED OF ETS1, RUNX1, CBFBETA, AND THE TCRALPHA GENE ENHANCER DNA
referenceShiina et al. J.Mol.Biol. 427 1655 2015
experimentX-ray (resolution=2.35, R-factor=0.249)
structural superfamilyp53-like transcription factors;
sequence familyRunt domain;
multimeric complexes3wts_AC 3wtt_AC 3wtu_AC 3wtv_AC 3wtw_AC 3wtx_AC 3wty_AC 3wu1_AB 4l0y_AB 4l0z_AB 4l18_AB 4l18_EF
reference complex4l18_E
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRVDRR

Estimated binding specificities ?

readout + contactlogo
# IC=4.434 IC/col=0.887 n_of_columns=5 specificity:   
A |   0   0  54   0  54
C |  96  96  16  96  13
G |   0   0  13   0  16
T |   0   0  13   0  13
scan!

home
updated Thu Jan 8 23:37:13 2026