interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE COMPLEX COMPRISED OF ETS1(V170G), RUNX1, CBFBETA, AND THE TCRALPHA GENE ENHANCER DNA
(RUNT-RELATED TRANSCRIPTION FACTOR 1)
referenceShiina et al. J.Mol.Biol. 427 1655 2015
sourceMUS MUSCULUS
experimentX-ray (resolution=2.70, R-factor=0.242)
structural superfamilyp53-like transcription factors;
sequence familyRunt domain;
multimeric complexes3wts_AC 3wtt_AC 3wtu_AC 3wtv_AC 3wtw_AC 3wtx_AC 3wty_AC
reference complex3wts_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRDRR

Estimated binding specificities ?

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# IC=5.766 IC/col=0.961 n_of_columns=6 specificity:   
A |  13   0  16   0   0   0
C |  13   0  13   0   0  96
G |  16  96  13  96  96   0
T |  54   0  54   0   0   0
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updated Thu Sep 12 18:38:35 2024