interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE COMPLEX COMPRISED OF ETS1(G333P), RUNX1, CBFBETA, AND THE TCRALPHA GENE ENHANCER DNA
referenceShiina et al. J.Mol.Biol. 427 1655 2015
experimentX-ray (resolution=2.70, R-factor=0.227)
structural superfamilyp53-like transcription factors;
sequence familyRunt domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRVDRR

Estimated binding specificities ?

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# IC=5.419 IC/col=0.903 n_of_columns=6 specificity:   
A |  10   0  10   0   0  12
C |  12   0   0   0   0  64
G |  10  96  12  96  96  10
T |  64   0  74   0   0  10
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updated Mon Dec 16 22:35:50 2024