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structure nameASYMMETRIC DNA-BENDING IN THE CRE-LOXP SITE-SPECIFIC RECOMBINATION SYNAPSE
(PROTEIN CRE RECOMBINASE)
referenceVan Duyne et al.
sourceEnterobacteria phage P1
experimentX-ray (resolution=2.20, R-factor=0.213)
structural superfamilyDNA breaking-rejoining enzymes;lambda integrase-like, N-terminal domain;
sequence familyPhage integrase family;
multimeric complexes1kbu_AB 1ma7_AB 1nzb_AB 1pvp_AB 1pvq_AB 1pvr_AB 1xo0_AB 2hof_AB 2hoi_GH 3c28_AB 3c29_AB 4crx_AB 5crx_AB 7rhx_AB 7rhz_AB
reference complex7rhx_G
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHTMSKTQQKRRKSRER

Estimated binding specificities ?

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# IC=11.599 IC/col=0.828 n_of_columns=14 specificity:   
A |  75   6  89  24  24  24   6   0   0   6  96   0  96   0
C |   9   9   0  24  24  24   6  96   0   9   0   0   0   0
G |   6   6   7  24  24  24   6   0  96   6   0   0   0  96
T |   6  75   0  24  24  24  78   0   0  75   0  96   0   0
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updated Fri Jan 9 00:02:50 2026