interface graph thumbnail
legend  pdf

3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameHUMAN MHF1 MHF2 DNA COMPLEXES
(CENTROMERE PROTEIN X)
referenceSachpatzidis et al. 'Nat 5 2987 2014
sourceHOMO SAPIENS
experimentX-ray (resolution=6.50, R-factor=0.267)
structural superfamilyHistone-fold;
sequence familyProtein of unknown function DUF2008;
multimeric complexes4ndy_IKLM 4ndy_QTUV 4ne1_IKf 4ne1_LMj 4ne1_QTUV 4ne1_Wknop 4ne1_hi
redundant complexes4ndy_L
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  RAETRT--                            +4ne1_p    
                                    +-3 
  --IT--RA                    +-----4 +7k78_E    
                              !     ! 
  ------RT                 +--5     +7wlr_E    
                           !  ! 
  ------RA                 !  !      +6t7a_C    
                 +---------6  +------1 
  ------RT       !         !         +7lyb_G    
                 !         ! 
  ------RT     --7         !         +7lya_E    
                 !         +---------2 
  ------RT       !                   +7zs9_e    
                 ! 
  ------RT       +-------------------1u35_G    
               

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updated Thu Dec 22 20:32:19 2022