4roc_A : 3D-footprint complex

structure name	HUMAN TFIIB-RELATED FACTOR 2 (BRF2) AND TBP BOUND TO U6#2 PROMOTER (TRANSCRIPTION FACTOR IIIB 50 KDA SUBUNIT)
reference	Guthertz et al. 'Cell(Cambridge,Mass.)' 163 1375 2015
source	HOMO SAPIENS
experiment	X-ray (resolution=1.90, R-factor=0.187)
structural superfamily	Cyclin-like;
multimeric complexes	4roc_AB 4rod_AB 4roe_AB 5n9g_AC 5n9g_FH
redundant complexes	4rod_A 4roe_A 5n9g
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4roc_A interface=44,46,196, vsrsqqrglrrvrdlcrvlqlpptfedtavayyqqayrhsgirAaRlqkkevlvgccvlitcrqhnwpltmgaictllyadldvfsstymqivkllgldvpslclaelvktycssfklfqaspsvpakyvedkekmlsrtmqlvelanetwlvtgrhplpvitaatflawqslqpadrlscslarfcklanvdlpYpassrlqellavllrmaeqlawlrvlrldkrsvvkhigdllqhrqslvrsafrdlllppcmlkspkricpvppvstvtgdenisdseieqylrtpqevrdfqraqa
interface signature	ARY

Estimated binding specificities ?

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# IC=4.007 IC/col=0.250 n_of_columns=16

specificity:

A |   0   0  24  24  24  24  24  24  24  24  24  24  24   9   9  11
C |   0   0  24  24  24  24  24  24  24  24  24  24  24  11   9   9
G |  96  96  24  24  24  24  24  24  24  24  24  24  24  67   9  67
T |   0   0  24  24  24  24  24  24  24  24  24  24  24   9  69   9

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --ACRC------------YC------   L                      +------------4roc_A    
                                             +--------1 
  QT------------------EG----           +-----2        +------------6f40_V    
                                       !     ! 
  ----------------------VCTC         +-3     +---------------------7nvu_M    
                                     ! ! 
  ------------RG--YG--------       +-4 +---------------------------1qbj_C    
                                   ! ! 
  ------SGRGPTSGRG----------   L --5 +----------------------------7bhy_A    
                                   ! 
  ------------RC--YG--------       +----------------------------2acj_B

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updated Thu Dec 22 20:43:16 2022