| structure name | BINARY COMPLEX OF HUMAN POLYMERASE NU AND DNA WITH THE FINGER DOMAIN CLOSED (DNA polymerase nu) |
| reference | Lee et al. Nat.Struct.Mol.Biol. 22 298 2015 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.95, R-factor=0.223) |
| structural superfamily | DNA/RNA polymerases;Ribonuclease H-like; |
| sequence family | DNA polymerase family A; |
| redundant complexes | 4xvi_A 4xvl_A 4xvm_A |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | KREKYAYARNQH |
Estimated binding specificities ?
readout + contact |  |
A | 13 16 24 24 0 0 C | 54 13 24 24 0 0 G | 13 13 24 24 96 96 T | 16 54 24 24 0 0scan! |
Dendrogram of similar interfaces ?
matrix format------------------------KT------------RG----EGKGYGACYCAC----RC----------QTATRTNGQGHC L +-----4xvk_A +-------------5 ------------------------NA--KG--------RC--NT--QC--------------------NG--YGATRT--QGHC ! +-----4x0p_B ! --------------------------RC----------RANG------YG--YT--SCYC------------------NTQT-- L ! +-6vdd_A ! +-1 ------------------------KT----YG------RGNG------YG--YAIGSCYC----NGRC--FG--------QAHG ! +--2 +-4yfu_D +--------8 ! ! NG--KGYGMG--RC--EG--------------SGHGVC---------------------------------------------- ! ! +--4 +-1kln_A ! ! ! ! ------------------AAVAAAKC------------RTNG----TC----YCMCSAHARAQAEA------------NGQG-- ! ! ! ! +--6fbc_A ! ! +--------6 +-3 ----------------------------------------NA------FC--YG------RG--------------RGNGQC-- L --9 ! ! ! +--1tau_A ! +--7 ! ----------------------------KA------------NT------------------------------------QGHT L ! ! +-------6xbu_A ! ! --------------------------------------RTNGQG---------------------------------------- ! +----------------1x9m_A ! --EC------DA--FA-------------------------------------------------------------------- +----------------------------3qex_A |
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updated Fri Sep 13 18:58:56 2024