interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF REDUCED ABFR BOUND TO DNA
(MarR family transcriptional regulator)
referenceYang et al. 'J. 139 1598 2017
sourceStaphylococcus epidermidis
experimentX-ray (resolution=3.00, R-factor=0.228)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyMarR family;
multimeric complexes5hlg_AC 5hlg_FH 5hlh_AC 5hlh_FH
redundant complexes5hlh_D
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSNTTPR

Estimated binding specificities ?

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# IC=8.247 IC/col=0.916 n_of_columns=9 specificity:   
A |   0   0  24  60  84   0   0   0  12
C |  96   0  24  12  12   0  96   0  60
G |   0   0  24  12   0   0   0  96  12
T |   0  96  24  12   0  96   0   0  12
scan!

Dendrogram of similar interfaces ?

matrix format
  
  ----RGSTRTSTHG------RA----   L                                   +3zpl_B    
                                     +-----------------------------1 
  --DCLT--AGTTRG--RG--RA----   L   +-2                             +5h3r_A    
                                   ! ! 
  TT----KATTQTTGLTRTKA--FTYT   L --3 +-----------------------------2p7c_B    
                                   ! 
  --------------YG----------       +-----------------------------3eyi_B

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updated Fri Sep 13 19:45:00 2024