| structure name | CRYSTAL STRUCTURE OF HUMAN DUX4 HOMEODOMAINS BOUND TO A12T DNA MUTANT (Double homeobox protein 4-like protein 4) |
| reference | Gan et al. 'Biochem. 505 1161 2018 |
| source | Homo sapiens |
| experiment | X-ray (resolution=1.90, R-factor=0.188) |
| structural superfamily | Homeodomain-like; |
| sequence family | Homeobox domain; |
| redundant complexes | 5z6z_A
5zfw_A
5zfy_A
 6e8c_A
6u81_A
6u82_A
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | RRIQNRSRRIQNAR |
Estimated binding specificities ?
| readout + contact |  |
A | 12 0 96 96 0 0 10 24 0 0 0 96 C | 53 0 0 0 21 96 21 24 0 0 96 0 G | 21 0 0 0 1 0 10 24 0 0 0 0 T | 10 96 0 0 74 0 55 24 96 96 0 0scan! |
Dendrogram of similar interfaces ?
matrix formatKGRT--IAQCNAYA--RT-------------------- L +-----------------------------1nk2_P +-1 RCRT--NT--NAITRG---------------------- +-2 +-----------------------------5zjt_B ! ! --RT--NT--NAIARG---------------------- L +-3 +-----------------------------1b72_B ! ! --RTFTYAQTNAATRG---------------------- L +-4 +-----------------------------6ryd_F ! ! --------------------------RTVAITNAMCRG L +-5 +-----------------------------1yrn_A ! ! ------------------RT--RT----IAKGNA---- L +-6 +-----------------------------6m3d_C ! ! --------------------RC--RT--NCSTNARG-- L --7 +-----------------------------1mnm_C ! --RA--YAQTNAAARG---------------------- L +-----------------------------6wig_A |
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updated Sun Aug 3 10:46:10 2025