interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF STREPTOCOCCUS THERMOPHILUS SHP PHEROMONE RECEPTOR RGG3 BOUND TO DNA
(Positive transcriptional regulator MutR family)
referenceCapodagli et al. Proc.Natl.Acad.Sci.USA 117 24494 2020
sourceStreptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) / Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
experimentX-ray (resolution=3.20, R-factor=0.222)
structural superfamilylambda repressor-like DNA-binding domains;
multimeric complexes6w1f_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureCSKSQSR

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5 specificity:   
A |   0   0   0  13  54
C |   0   0   0  16  13
G |   0  96  96  54  13
T |  96   0   0  13  16
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --CTSGKTSGQTSTRC------   L                          +6w1f_A    
                                             +--------2 
  ----SGKGSCQTSTRG------   L          +------4        +6w1a_A    
                                      !      ! 
  ----HCQASTETSARG----VT   L   +------5      +---------3u3w_B    
                               !      ! 
  ------------ITRG------   L   !      +----------------5jub_B    
                             --6 
  ----STNTVTATSTQTRTETTT   L   !                        +2r1j_L    
                               !                      +-1 
  AT--ATTTPTTTNT--------   L   +----------------------3 +6fix_D    
                                                      ! 
  ----AAKGSGYGST--RTQG--   L                          +3zkc_A    
                             

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updated Tue Dec 19 15:41:04 2023