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structure nameCRYSTAL STRUCTURE OF BACILLUS THURINGIENSIS PLCR IN COMPLEX WITH THE PEPTIDE PAPR7 AND DNA
(Transcriptional activator PlcR protein)
referenceBouillaut et al. Proc.Natl.Acad.Sci.USA 110 1047 2013
sourceBacillus thuringiensis
experimentX-ray (resolution=2.40, R-factor=0.182)
structural superfamilylambda repressor-like DNA-binding domains;TPR-like;
sequence familyHelixturnhelix;
multimeric complexes3u3w_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHQSESRV

Estimated binding specificities ?

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# IC=5.651 IC/col=0.942 n_of_columns=6 specificity:   
A |  27  13   0   0  96  96
C |  15  13   0   0   0   0
G |  13  54   0  96   0   0
T |  41  16  96   0   0   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: PLCR
TATGCATTATTTCATAPubMed3u3w_B(3.68e-04), 3u3w_AB(7.89e-12)

Dendrogram of similar interfaces ?

matrix format
  
  ------HCQASTETSARG----VT----   L                  +----------3u3w_B    
                                     +--------------5 
  ----CTSGKTSGQTSTRC----------   L   !              !         +6w1f_A    
                                     !              +---------3 
  ------SGKGSCQTSTRG----------   L   !                        +6w1a_A    
                                     ! 
  --QT--STNTVTATSTQTRTETTT----   L   !                         +2r1j_L    
                                   --8            +------------1 
  ----RTTT--AT--STRG----TT----   L   !            !            +6chv_D    
                                     !      +-----6 
  ----AT--QAAT--SA------------       !      !     !            +4z5h_A    
                                     !      !     !      +-----2 
  ----STKCQAAT--SA------------   L   +------7     +------4     +3dnv_B    
                                            !            ! 
  RT--------RG----NT----ETRTYA   L          !            +-----7f9h_B    
                                            ! 
  ----ATATTTPTTTNT------------   L          +------------------6fix_D    
                                   

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updated Wed Dec 18 00:00:58 2024