interface graph thumbnail
legend  pdf

3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameSTRUCTURE OF HUMAN CGAS (K394E) BOUND TO THE NUCLEOSOME
(HISTONE H3.2)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes6y5d_ABCDEFGH 6y5d_KMNOPQRST
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  --RT----         +-----------------------------8grq_A    
                 +-9 
  LCRT----       ! +-----------------------------8hr1_E    
                 !  
  --RA----       !                          +--7xsx_a    
                 !                  +-------4 
  ----RA--       !                  !       +--6g0l_D    
               -10                +-5 
  --RA----       !                ! !         +1zla_C    
                 !                ! +---------3 
  --RA--RA       !             +--6           +6a5l_g    
                 !             !  ! 
  --RG----       !             !  !            +8txv_G    
                 !             !  +------------2 
  --RG----       +-------------8               +8ox0_C    
                               ! 
  --RT----                     !                 +8u14_G    
                               ! +---------------1 
  --RG----                     +-7               +5x0y_G    
                                 ! 
  --RG----                       +---------------8jla_C    
               

home
updated Sun Aug 3 14:30:08 2025