interface graph thumbnail
legend  pdf

3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameSTRUCTURE OF HUMAN CGAS (K394E) BOUND TO THE NUCLEOSOME
(HISTONE H3.2)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes6y5d_ABCDEFGH 6y5d_KMNOPQRST
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  LCRT----         +-----------------------------8hr1_E    
                 +-9 
  --RT----       ! +-----------------------------8grq_A    
                 !  
  --RA----       !                          +--7xsx_a    
                 !                  +-------4 
  ----RA--       !                  !       +--6g0l_D    
               -10             +----5 
  --RA----       !             !    !          +1zla_C    
                 !         +---7    +----------2 
  --RG----       !         !   !               +8ox0_C    
                 !         !   ! 
  --RG----       !         !   +---------------8jla_C    
                 +---------8 
  --RT----                 !                   +8u14_G    
                           !    +--------------1 
  --RG----                 !    !              +5x0y_G    
                           +----6 
  --RG----                      !              +8txv_G    
                                +--------------3 
  --RA--RA                                     +6a5l_g    
               

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updated Wed Dec 18 07:01:58 2024