7bzg_B : 3D-footprint complex

structure name	STRUCTURE OF BACILLUS SUBTILIS HXLR, WILD TYPE IN COMPLEX WITH FORMALDEHYDE AND DNA (HTH-type transcriptional activator HxlR)
reference	Chen et al. 'Nat 12 581 2021
source	Bacillus subtilis (strain 168) / Bacillus subtilis (strain 168)
experiment	X-ray (resolution=2.90, R-factor=0.181)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	HxlRlike helixturnhelix;
multimeric complexes	7bzg_AB 7bzg_EF 7bzg_IJ
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 7bzg_B interface=39,40,50,51,52,53,55,77, srmddkrfncekeltlaviggkwkmlilwhlgkegtkrFNelktlipdiTQKIlVnqlreleqdmivhrevypvvpPkveysltphgeslmpileamyewgkgymelidi
interface signature	FNTQKIVP

Estimated binding specificities ?

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# IC=6.313 IC/col=0.902 n_of_columns=7

specificity:

A |   0  90   0  79   5   5   5
C |   0   0   7   5  90  11   5
G |  96   6   5   7   0  16  81
T |   0   0  84   5   1  64   5

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ----RGSTRTSTHG------RA----   L                                       +3zpl_B    
                                         +-----------------------------1 
  --DCLT--AGTTRG--RG--RA----   L       +-2                             +5h3r_A    
                                       ! ! 
  ------KATTQTTGLTRTKAFT--YT   L     +-3 +-----------------------------2p7c_B    
                                     ! ! 
  --SG--PTPGTT----------HG--   L   +-4 +-----------------------------7d98_Q    
                                   ! ! 
  LANTHGTTETYTRG------------   L --5 +-----------------------------1f4k_B    
                                   ! 
  --------------YG----------       +-----------------------------3eyi_B

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updated Sat Sep 14 01:59:52 2024