interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF BACILLUS SUBTILIS HXLR, WILD TYPE IN COMPLEX WITH FORMALDEHYDE AND DNA
(HTH-type transcriptional activator HxlR)
referenceChen et al. 'Nat 12 581 2021
sourceBacillus subtilis (strain 168) / Bacillus subtilis (strain 168)
experimentX-ray (resolution=2.90, R-factor=0.181)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyHxlRlike helixturnhelix;
multimeric complexes7bzg_AB 7bzg_EF 7bzg_IJ
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureFNTQKIVP

Estimated binding specificities ?

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# IC=6.385 IC/col=0.912 n_of_columns=7 specificity:   
A |   0  89   6  83   6   6   0
C |   0   0   0   0  89  19   7
G |  96   6   6   7   1  14  83
T |   0   1  84   6   0  57   6
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --------------------------------RT                   +-----------------------------3gfi_A    
                                                     +-1 
  ------TC--STKTPTTTFT------------RT               +-2 +-----------------------------4ass_H    
                                                   ! ! 
  ----------TT--RGRT--------SGRT--KT   L         +-3 +-----------------------------2v1u_A    
                                                 ! ! 
  ----------DCLT--AGTTRG--RG------RA   L       +-4 +-----------------------------5h3r_A    
                                               ! ! 
  ------YC--KTHGSTQTYTPT--------LG--   L     +-5 +-----------------------------5x11_A    
                                             ! ! 
  ------SGQG--YCNC------------------       +-6 +-----------------------------2ve9_C    
                                           ! ! 
  ----------------------YG----------     --7 +-----------------------------2heo_D    
                                           ! 
  RGRTKG----------------------------   L   +-----------------------------6lui_A    
                                         

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updated Tue Dec 19 17:43:03 2023