interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF NF-KB P52 HOMODIMER BOUND TO P-SELECTIN KB DNA FRAGMENT
(Nuclear factor NF-kappa-B p52 subunit)
referenceMeshcheryakov et al. 'To ? ? ?
sourceHomo sapiens
experimentX-ray (resolution=3.00, R-factor=?)
structural superfamilyp53-like transcription factors;E set domains;
sequence familyRel homology domain RHD; IPT/TIG domain;
multimeric complexes7cli_AB 7vup_AB 7vuq_AB 7w7l_AB
redundant complexes7vup_A 7vuq_A 7w7l_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRYCESHK

Estimated binding specificities ?

readout + contactlogo
# IC=3.966 IC/col=0.991 n_of_columns=4 specificity:   
A |   9   2   0   6
C |  84  89  95  81
G |   2   3   1   5
T |   1   2   0   4
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RGRGYACCEC----SAHG------KG------------   L                                   +7cli_B    
                                                                             +-2 
  RGRGYA--EC------HG------KG------------   L                           +-----4 +7w7l_B    
                                                                       !     ! 
  RGRGYTCCEC------HG------KG------------   L                           !     +1a3q_A    
                                                         +-------------8 
  RCRCYC--EC------HC------KT------RG----   L             !             !      +1svc_P    
                                                         !             ! +----1 
  RGRGYTCCEC------HTKT----KT--PTKTRG----   L             !             ! !    +1nfk_A    
                                                         !             +-7 
  RGRGYTCCEC--------------KT------------   L             !               !    +2v2t_A    
                                                  +-----10               +----5 
  RGRGYTCTEC--------------RT------------   L      !      !                    ! +1gji_A    
                                                  !      !                    +-3 
  RGRG----EC--------------RG--PTKT------   L      !      !                      +2ram_A    
                                                  !      !  
  RGRG----EG--RG------------------------   L   +-11      !     +-------------1bvo_A    
                                               !  !      +-----9 
  RG--YT--TTEC----RG----------QA--------   L   !  !            +-------------1imh_C    
                                               !  !  
  RGRGYT--EC----------KTTTQART----------   L -12  !                         +1a66_A    
                                               !  +-------------------------6 
  RG--YT--TTEC----RG------QA------------   L   !                            +1p7h_L    
                                               !  
  ----------------------------------RAVC   L   +----------------------------6vgd_D    
                                             

home
updated Sat Sep 14 02:05:43 2024