3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameCRYO-EM STRUCTURE OF THE HUMAN NUCLEOSOME CORE PARTICLE UBIQUITYLATED AT HISTONE H2A LYS13 AND LYS15 IN COMPLEX WITH BARD1 (RESIDUES 415- 777)
(HISTONE H2A TYPE 1-BE)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes6nqa_ABCDEFGH 7lyc_ABCDEFGH 8txw_ABCDEFGH 8txx_ABCDEFGH
redundant complexes6nqa 8txv 8txw 8txx
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  --RT----                                 +8smw_G    
                            +--------------1 
  --RG----                  !              +5x0y_G    
                          +-6 
  --RT----                ! !              +8u14_G    
                        +-7 +--------------2 
  --RG----              ! !                +8ox0_C    
                        ! ! 
  --RA--RA              ! +---------------6a5l_g    
                      +-8 
  --RG----            ! !                 +8txv_G    
                      ! !     +-----------3 
  --RA----       +----9 +-----5           +1zla_C    
                 !    !       ! 
  --RT----       !    !       +-----------8grq_A    
                 !    ! 
  --RG----     -11    +------------------8jla_C    
                 !  
  --RG--RG       !                +------8kcb_A    
                 !   +------------4 
  ----RA--       +--10            +------6g0l_D    
                     !  
  LCRT----           +-------------------8hr1_E

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updated Wed Dec 18 09:44:23 2024