3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameCRYO-EM STRUCTURE OF THE HUMAN NUCLEOSOME CORE PARTICLE UBIQUITYLATED AT HISTONE H2A LYS13 AND LYS15 IN COMPLEX WITH BARD1 (RESIDUES 415- 777)
(HISTONE H2A TYPE 1-BE)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes6nqa_ABCDEFGH 7lyc_ABCDEFGH 8txw_ABCDEFGH 8txx_ABCDEFGH
redundant complexes6nqa 8txv 8txw 8txx
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  --RT----                                 +8u14_G    
                            +--------------1 
  --RG----                  !              +5x0y_G    
                          +-6 
  --RG----                ! !              +8txv_G    
                       +--7 +--------------2 
  --RG----             !  !                +8ox0_C    
                       !  ! 
  --RA--RA             !  +--------------6a5l_g    
                     +-8 
  --RT----           ! !                 +8smw_G    
                     ! !      +----------3 
  --RA----       +---9 +------5          +1zla_C    
                 !   !        ! 
  LCRT----       !   !        +----------8hr1_E    
                 !   ! 
  --RG----     -11   +------------------8jla_C    
                 !  
  --RG--RG       !               +------8kcb_A    
                 !   +-----------4 
  ----RA--       +--10           +------6g0l_D    
                     !  
  --RT----           +------------------8grq_A

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updated Sun Aug 3 17:04:54 2025