3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameCRYO-EM STRUCTURE OF THE HUMAN NUCLEOSOME CORE PARTICLE UBIQUITYLATED AT HISTONE H2A LYS13 AND LYS15 IN COMPLEX WITH BARD1 (RESIDUES 415- 777)
(HISTONE H2A TYPE 1-BE)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes6nqa_ABCDEFGH 7lyc_ABCDEFGH
redundant complexes6nqa
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
  
  --------RT                 +-----------------------------7lyb_G    
                           +-2 
  --------RA             +-3 +-----------------------------6t7a_C    
                         ! ! 
  KA------RT           +-4 +-----------------------------1u35_G    
                       ! ! 
  --RAETRT--         +-5 +-----------------------------4ne1_p    
                     ! ! 
  --------RT       +-6 +-----------------------------7lya_E    
                   ! ! 
  --------RT     --7 +-----------------------------7wlr_E    
                   ! 
  ----IT--RA       !                            +7k78_E    
                   +----------------------------1 
  --------RT                                    +7zs9_e

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updated Tue Dec 19 18:58:26 2023