interface graph thumbnail
legend  pdf

structure nameTHE GLUCOCORTICOID RECEPTOR IN COMPLEX WITH VELSECORAT, A PGC1A COACTIVATOR FRAGMENT AND SGK 23BP
(Glucocorticoid receptor)
referenceWissler et al. Nat.Struct.Mol.Biol. 30 286 2023
sourceHomo sapiens
experimentX-ray (resolution=2.50, R-factor=0.205)
structural superfamilyNuclear receptor ligand-binding domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyLigandbinding domain of nuclear hormon; Zinc finger, C4 type two domains;
multimeric complexes7prv_AB 7prw_AB
redundant complexes7prv_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVR

Estimated binding specificities ?

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# IC=1.678 IC/col=0.336 n_of_columns=5 specificity:   
A |  15  21  38   6  81
C |  15  21  20  78   7
G |  49  33  19   6   4
T |  17  21  19   6   4
scan!

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updated Sun Aug 3 18:16:57 2025