interface graph thumbnail
legend  pdf

structure nameTHE GLUCOCORTICOID RECEPTOR IN COMPLEX WITH VELSECORAT, A PGC1A COACTIVATOR FRAGMENT AND SGK 23BP
(Glucocorticoid receptor)
referenceWissler et al. Nat.Struct.Mol.Biol. 30 286 2023
sourceHomo sapiens
experimentX-ray (resolution=2.50, R-factor=0.205)
structural superfamilyNuclear receptor ligand-binding domain;Glucocorticoid receptor-like DNA-binding domain;
sequence familyLigandbinding domain of nuclear hormon; Zinc finger, C4 type two domains;
multimeric complexes7prv_AB 7prw_AB
redundant complexes7prv_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVR

Estimated binding specificities ?

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# IC=3.101 IC/col=0.620 n_of_columns=5 specificity:   
A |   0   0  13  24  13
C |   0   0  13  24  54
G |   0  96  16  24  13
T |  96   0  54  24  16
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updated Wed Dec 18 10:58:35 2024