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legend  pdf

structure nameCRYSTAL STRUCTURE OF CRX-RET4 OLIGONUCLEOTIDE COMPLEX
(Cone-rod homeobox protein)
referenceSrivastava et al. 'To ? ? ?
sourceHomo sapiens
experimentX-ray (resolution=2.90, R-factor=0.253)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes9b8u_AB 9b8u_CD
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRVKN

Estimated binding specificities ?

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# IC=6.453 IC/col=0.922 n_of_columns=7 specificity:   
A |  52   0  17   0   8  96   0
C |  17   0  52   0   2   0   0
G |  17  96  19   0   8   0  96
T |  10   0   8  96  78   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RTQTVAQTNA--------   L                                   +8osb_E    
                                           +---------------1 
  RT--VTKGNA----KA--   L                 +-3               +2lkx_A    
                                         ! ! 
  ----NCICRGRG------   L         +-------4 +---------------4xrm_B    
                                 !       ! 
  RT--IAQCNA--MG----   L         !       !           +----1b72_A    
                               +-5       +-----------2 
  RC--IAQCNA--YC----   L       ! !                   +----3rkq_B    
                           +---6 ! 
  ----VTCCNA--QA--RT   L   !   ! +------------------------8g87_X    
                         --7   ! 
  ------------YCFAKC       !   +-------------------------6pe2_B    
                           ! 
  RT----YTNC----NAKG   L   +-----------------------------8pi8_B    
                         

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updated Sat Sep 14 12:46:30 2024