interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF CRX-RET4 OLIGONUCLEOTIDE COMPLEX
(Cone-rod homeobox protein)
referenceSrivastava et al. 'To ? ? ?
sourceHomo sapiens
experimentX-ray (resolution=2.90, R-factor=0.253)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes9b8u_AB 9b8u_CD
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRVKN

Estimated binding specificities ?

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# IC=6.602 IC/col=0.943 n_of_columns=7 specificity:   
A |   0   0  76  96   9   0   9
C |  96   0   2   0  21  96  19
G |   0   0   9   0  57   0   9
T |   0  96   9   0   9   0  59
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RTQTVAQTNA--------   L                                    +8osb_E    
                                            +---------------1 
  RT--VTKGNA----KA--   L                +---2               +2lkx_A    
                                        !   ! 
  RT--IAQCNA--MG----   L            +---3   +---------------1b72_A    
                                    !   ! 
  ----NCICRGRG------   L          +-4   +-------------------4xrm_B    
                                  ! ! 
  RC--IAQCNA--YC----   L     +----5 +-----------------------3rkq_B    
                             !    ! 
  ----VTCCNA--QA--RT   L   +-6    +------------------------8g87_X    
                           ! ! 
  ------------YCFAKC   L --7 +-----------------------------6pe2_B    
                           ! 
  RT----YTNC----NAKG   L   +-----------------------------8pi8_B    
                         

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updated Wed Dec 18 20:09:26 2024