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legend  pdf

structure nameEVEN-SKIPPED HOMEODOMAIN COMPLEXED TO AT-RICH DNA
(Segmentation Protein Even-Skipped)
referenceAggarwal et al. 'EMBO 14 6280 1995
sourceDrosophila melanogaster
experimentX-ray (resolution=2.00, R-factor=?)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes1jgg_AB
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRYRVQNMKR

Estimated binding specificities ?

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# IC=3.426 IC/col=0.856 n_of_columns=4 specificity:   
A |  96   0   9  37
C |   0   1  10   6
G |   0   1   5  47
T |   0  94  72   6
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: EVEN-SKIPPED
TCAATTAAATPubMed1jgg_AB(9.82e-08)
AACAATPubMed1jgg_B(3.15e-03)

Dendrogram of similar interfaces ?

matrix format
  
  RT--IA----QCNA--MG------   L                             +---1b72_A    
                                              +------------2 
  RT--VT----KGNA----KA----   L                !            +---2lkx_A    
                                      +-------4 
  RTQTVA----QTNA----------   L        !       !                 +8osb_E    
                                      !       ! +---------------1 
  ----NC----ICNA--RGRG----   L   +----5       +-3               +4xrm_B    
                                 !    !         ! 
  RC--IA----QCNA--YC------   L   !    !         +----------------3rkq_B    
                               --6    ! 
  ----VT----CCNA--QA----RT   L   !    +------------------------8g87_X    
                                 ! 
  RT----YTNC----NA----KG--   L   +-----------------------------8pi8_B

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updated Fri Sep 13 15:42:52 2024