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legend  pdf

structure nameTHREE-DIMENSIONAL STRUCTURE OF S.AUREUS METHICILLIN-RESISTANCE REGULATING TRANSCRIPTIONAL REPRESSOR MECI IN COMPLEX WITH 25-BP DS- DNA
(Methicillin resistance regulatory protein mecI)
referenceMallorqui-Fernandez et al.
sourceStaphylococcus aureus subsp. aureus
experimentX-ray (resolution=2.80, R-factor=0.216)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyPenicillinase repressor;
multimeric complexes1sax_AB 2d45_AB 2d45_CD
redundant complexes2d45_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKTRTLR

Estimated binding specificities ?

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# IC=5.334 IC/col=0.762 n_of_columns=7 specificity:   
A |  19  96  24   0  96   0  59
C |  11   0  24  29   0  96   9
G |   9   0  24   0   0   0   9
T |  57   0  24  67   0   0  19
scan!

Dendrogram of similar interfaces ?

matrix format
  
  TT------KATT--QTTG--LTRT----KA----FTYT   L         +-----------------------------2p7c_B    
                                                   +-3 
  ----DCLT--AG--TTRG----RG--------RA----   L     +-4 +-----------------------------5h3r_A    
                                                 ! ! 
  --------------------YG----------------         ! +-----------------------------3eyi_B    
                                               +-5 
  --------------NASTRTHT--ST------------   L   ! !                         +---3l2c_A    
                                               ! !                   +-----1 
  --------------NASTRGHT--STLT----------   L --6 +-------------------2     +---7cby_C    
                                               !                     ! 
  --LANTHGTTET--YTRG--------------------   L   !                     +---------1f4k_B    
                                               ! 
  ------PTPG--TT----------------HG------   L   +-----------------------------7d98_Q    
                                             

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updated Fri Sep 13 15:59:49 2024