| structure name | PHAGE-SELECTED HOMEODOMAIN BOUND TO UNMODIFIED DNA (Segmentation polarity homeobox protein engrailed) |
| reference | Feldman et al. 'Acs 1 755 2006 |
| source | Drosophila melanogaster |
| experiment | X-ray (resolution=1.90, R-factor=0.225) |
| structural superfamily | Homeodomain-like; |
| sequence family | Homeobox domain; |
| multimeric complexes | 2hos_AB 2hot_AB |
| redundant complexes |  2hot_A
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | RKN |
Estimated binding specificities ?
| readout + contact |  |
A | 8 0 69 0 11 87 C | 8 0 8 0 8 1 G | 72 96 11 0 8 8 T | 8 0 8 96 69 0scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: ENGRAILED | ||
| TAATTA | PubMed | 2hos_A(1.21e-03), 2hot_A(3.57e-04) |
| TAATCC | PubMed | 2hos_A(4.53e-11), 2hos_AB(6.43e-08), 2hot_AB(5.23e-08), ... (total=4) |
| CGCATCCCC | PubMed | 2hos_A(1.05e-02) |
| TTAATT | PubMed | 2hos_A(1.21e-03), 2hot_A(3.57e-04) |
| TAATNN | PubMed | 2hos_A(1.21e-03), 2hot_A(3.57e-04) |
Dendrogram of similar interfaces ?
matrix format--QTVAQTNA------ L +8osb_E +--1 ----VTKGNA--KA-- L ! +2lkx_A +-------------3 RT--NT--NAIARG-- L ! ! +4cyc_B ! +--2 ----NCITNARGRG-- L +---5 +6fqq_E ! ! ----IAQCNAMG---- L ! ! +----1b72_A +----6 +-----------4 ----IAQCNAYC---- L ! ! +----3rkq_B +-7 ! ----NCICRG------ L ! ! +--------------------4xrm_B --8 ! ----VTCCNAQA--RT L ! +-------------------------8g87_X ! ----------YCFAKC L +--------------------------6pe2_B |
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updated Mon Jun 29 15:10:19 2026