structure name | PHAGE-SELECTED HOMEODOMAIN BOUND TO UNMODIFIED DNA (Segmentation polarity homeobox protein engrailed) |
reference | Feldman et al. 'Acs 1 755 2006 |
source | Drosophila melanogaster |
experiment | X-ray (resolution=1.90, R-factor=0.225) |
structural superfamily | Homeodomain-like; |
sequence family | Homeobox domain; |
multimeric complexes | 2hos_AB 2hot_AB |
redundant complexes | ![]() |
links to other resources | NAKB ![]() |
protein sequence | |
interface signature | RKN |
Estimated binding specificities ?
readout + contact | ![]() |
A | 0 69 96 8 0 8 C | 8 8 0 8 96 72 G | 1 8 0 8 0 8 T | 87 11 0 72 0 8scan! |
Related DNA sequences reported in the literature ?
site | source | matches (E-value) |
---|---|---|
term: ENGRAILED | ||
TAATTA | PubMed | 2hos_A(1.21e-03), 2hot_A(3.57e-04) |
TAATCC | PubMed | 2hos_A(4.53e-11), 2hos_AB(6.43e-08), 2hot_AB(5.23e-08), ... (total=4) |
CGCATCCCC | PubMed | 2hos_A(1.05e-02) |
TTAATT | PubMed | 2hos_A(1.21e-03), 2hot_A(3.57e-04) |
TAATNN | PubMed | 2hos_A(1.21e-03), 2hot_A(3.57e-04) |
Dendrogram of similar interfaces ?
matrix format--VTKGNA--KA-- L +-----------------------------2lkx_A ! QTVAQTNA------ L ! +8osb_E ! +-1 --IAQCNAMG---- L ! +---------2 +1b72_A --6 ! ! --NCICRG------ L ! +----------3 +--4xrm_B ! ! ! --IAQCNAYC---- L ! +-4 +------------3rkq_B ! ! ! --VTCCNAQA--RT L +---5 +-----------------------8g87_X ! --------YCFAKC L +-------------------------6pe2_B |
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updated Sun Aug 3 06:16:18 2025