4l62_M : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA TRANSCRIPTIONAL REGULATOR PA2196 BOUND TO ITS OPERATOR DNA (Transcriptional regulator)
reference	Choe et al. Biochem.Biophys.Res.Commun. 440 317 2013
source	Pseudomonas aeruginosa
experiment	X-ray (resolution=2.90, R-factor=0.200)
structural superfamily	Tetracyclin repressor-like, C-terminal domain;Homeodomain-like;
sequence family	Bacterial regulatory proteins, tetR family;
multimeric complexes	4l62_ABCD 4l62_EFGH 4l62_IJKL 4l62_MNOP
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4l62_M interface=27,38,40,42,43, syddtrqhlldtgyrimavkgfsgvgLneilqsagvpKgSfYHyfkskeqfgqalledyfrvyladmdqrfsapglnarerlmsywqkwldnacppcdeqrclvvklsaevadlsesmritlrdgsdgiierlvgclgqgrddgslapcdarhmasalyqlwlgasllsklhrspgpletamqttrslle
interface signature	LKSYH

Estimated binding specificities ?

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# IC=3.720 IC/col=0.620 n_of_columns=6

specificity:

A |   6   0   6  24  60  78
C |   6   0  78  24   6   6
G |  78   0   6  24  12   6
T |   6  96   6  24  18   6

scan!

Dendrogram of similar interfaces ?

matrix format

  
  LG----KG--STYTHT   L                   +-4l62_M    
                                         ! 
  LC--RTPTPTSTYT--   L     +-------------3   +6nsn_B    
                           !             ! +-1 
  ----TTRG----YTWA   L     !             +-2 +7jnp_A    
                         +-6               ! 
  VT--AGDT--TTYTLA   L   ! !               +5gpc_B    
                         ! ! 
  ----TCKGAG--YTHA     --7 +---------------5k7z_A    
                         ! 
  LTRG--PTAC--YT--   L   !       +---------3lsr_A    
                         !   +---4 
  ----TGKG----YCFA   L   +---5   +---------4pxi_B    
                             ! 
  MTRGTGPT--ATYTWT   L       +-------------5yej_B

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updated Fri Sep 13 18:27:53 2024