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structure nameTHE TRANSCRIPTIONAL REGULATOR PRFA-G145S MUTANT FROM LISTERIA MONOCYTOGENES IN COMPLEX WITH A 30-BP OPERATOR PRFA-BOX MOTIF
(Listeriolysin regulatory protein)
referenceSauer-Eriksson et al. 'Proc. 113 14733 2016
sourceListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) / Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
experimentX-ray (resolution=2.80, R-factor=0.233)
structural superfamilycAMP-binding domain-like;"Winged helix" DNA-binding domain;
multimeric complexes5lej_AB 5lek_AB 5lrs_AB 5x6d_GH 5x6d_MN 5x6e_EF 5x6e_MN 6qwf_AB 6qwh_AB 6qwk_AB 6qwm_AB
reference complex5lej_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHSASR

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5 specificity:   
A |  13  96  96  16  96
C |  13   0   0  54   0
G |  13   0   0  13   0
T |  57   0   0  13   0
scan!

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updated Fri Jan 9 04:00:56 2026