interface graph thumbnail
legend  pdf

structure nameTHE TRANSCRIPTIONAL REGULATOR PRFA FROM LISTERIA MONOCYTOGENES IN COMPLEX WITH GLUTATHIONE AND A 30-BP OPERATOR PRFA-BOX MOTIF
(Listeriolysin positive regulatory factor A)
referenceSauer-Eriksson et al. 'Proc. 113 14733 2016
sourceListeria monocytogenes
experimentX-ray (resolution=2.90, R-factor=0.249)
structural superfamilycAMP-binding domain-like;"Winged helix" DNA-binding domain;
multimeric complexes5lej_AB 5lek_AB 5lrs_AB 5x6d_GH 5x6d_MN 5x6e_EF 5x6e_MN 6qwf_AB 6qwh_AB 6qwk_AB 6qwm_AB
reference complex5lej_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHSASR

Estimated binding specificities ?

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# IC=5.766 IC/col=0.961 n_of_columns=6 specificity:   
A |  13  16  96  96   0  96
C |  16  13   0   0  96   0
G |  13  13   0   0   0   0
T |  54  54   0   0   0   0
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updated Sat Aug 2 09:14:16 2025