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legend  pdf

structure nameSTRUCTURES AND DYNAMICS OF MESOPHILIC VARIANTS FROM THE HOMING ENDONUCLEASE I-DMOI
(Homing endonuclease I-DmoI)
referenceMarcaida et al. 'J. 31 1063 2017
sourceDesulfurococcus mucosus
experimentX-ray (resolution=2.25, R-factor=0.198)
structural superfamilyHoming endonucleases;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYLYRSERVTQVDTRERSRRWHDDRHVL

Estimated binding specificities ?

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# IC=21.023 IC/col=1.168 n_of_columns=18 specificity:   
A |   8   0   0   0   0   0   0   8  61  88   0   8   0   0   0   0   0   0
C |   0   0  96  96   0   0   0   8  10   0   0   0   0  96  96   0   0  96
G |  10  96   0   0  96  96  96   8  17   8  96   1   0   0   0  96  96   0
T |  78   0   0   0   0   0   0  72   8   0   0  87  96   0   0   0   0   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  YAKGLG--RT----------QG--EC----------------------------------RT----KT   L                 +-----------------------------6x1j_A    
                                                                                         +-2 
  YGRGRG--------------QG--EC------------------------------------YCNGKG   L               ! !        +--------------------1r7m_B    
                                                                                       +-3 +--------1 
  CGRG--ST--TTKARGQTFA--QG--NG----------------HC--SC----LAQGRGQA------   L             ! !          +--------------------4yit_A    
                                                                                     +-4 ! 
  SAYCLC--------------------------------NA--RG----RG--DTIC--RG--------   L           ! ! +-----------------------------2fld_B    
                                                                                   +-5 ! 
  STIT----------QTST--AT--TC--------------------YT--------DTRGST------   L         ! ! +-----------------------------3mxb_B    
                                                                                 +-6 ! 
  SAIAQG--------QA----QA--TC------------------------------------------   L       ! ! +-----------------------------1t9i_B    
                                                                               +-7 ! 
  ----------------------------ACSTICICRCKCIC--EC----------RC----------   L     ! ! +-----------------------------1zzi_A    
                                                                             +-8 ! 
  STIGRG--------LTEC--ST--KG------------------TT--NA------MGRTSC------   L   ! ! +-----------------------------5t2n_A    
                                                                           --9 ! 
  ST--SC----RG--HTRT--TT--MT------------------LT--NC----YA----YA------   L   ! +-----------------------------7rcf_A    
                                                                             ! 
  SGIG----------RGQG--DG--TA----------------YC--AT--SC--VCKGRG--------   L   +-----------------------------6fb0_A    
                                                                           

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updated Fri Sep 13 20:11:01 2024