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structure nameTHE TRANSCRIPTIONAL REGULATOR PRFA-A94V MUTANT FROM LISTERIA MONOCYTOGENES IN COMPLEX WITH A 30-BP OPERATOR PRFA-BOX MOTIF
(Listeriolysin positive regulatory factor A)
referenceSauer-Eriksson et al. J.Bacteriol. 202 ? 2020
sourceListeria monocytogenes
experimentX-ray (resolution=2.70, R-factor=0.227)
structural superfamilycAMP-binding domain-like;"Winged helix" DNA-binding domain;
multimeric complexes5lej_AB 5lek_AB 5lrs_AB 5x6d_GH 5x6d_MN 5x6e_EF 5x6e_MN 6qwf_AB 6qwh_AB 6qwk_AB 6qwm_AB
redundant complexes6qwh 6qwk 6qwm 5lej 5lek 5lrs 5x6e 5x6d
reference complex5lej_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHSASR

Estimated binding specificities ?

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# IC=5.807 IC/col=0.968 n_of_columns=6 specificity:   
A |  13  16  96  96   0  96
C |  13  13   0   0  96   0
G |  13  13   0   0   0   0
T |  57  54   0   0   0   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: PRFA
TTAACATTTGTTAAPubMed6qwf_B(2.65e-04), 5lej_AB(1.89e-10), 5lek_AB(2.34e-08), ... (total=19)
TTAACAGCGTTTGTTAAPubMed6qwf_B(5.02e-04), 5lej_AB(3.76e-03), 5x6d_MN(1.35e-03), ... (total=13)
TTAACANNTGTTAAPubMed6qwf_B(2.65e-04), 5lej_AB(1.89e-10), 5lek_AB(2.34e-08), ... (total=19)

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updated Fri Sep 13 01:39:56 2024