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structure nameINTRON-ENCODED ENDONUCLEASE I-PPOI COMPLEXED WITH DNA
(INTRON 3 I-PPO ENCODED ENDONUCLEASE)
referenceMonnat Junior et al.
sourcePhysarum polycephalum
experimentX-ray (resolution=1.80, R-factor=0.208)
structural superfamilyHis-Me finger endonucleases;
multimeric complexes1a73_AB 1a74_AB 1cyq_AB 1cz0_AB 1evw_AB 1evw_CD 1ipp_AB 2o6m_AB
redundant complexes1a74_B 1cyq_A 1cz0_B 1evw_B 1ipp_A 2o6m_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureANRQKTVRLK

Estimated binding specificities ?

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# IC=9.064 IC/col=0.906 n_of_columns=10 specificity:   
A |   0   8  24   0   0   0   8   8   8   0
C |   0   0  24  96   0  96   8  72   8   8
G |   0  88  24   0   0   0   8   8   8   0
T |  96   0  24   0  96   0  72   8  72  88
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: PPOI
GGTCTCPubMed1cz0_AB(3.65e-03), 2o6m_AB(4.45e-03), 2o6m_B(5.49e-04), ... (total=4)

Dendrogram of similar interfaces ?

matrix format
  
  AANG--RAQAKGTTVTRG--LAKT   L        +-------------------1a73_A    
                                 +----2 
  QCPTDTYTRT--FA--TGQTQGVC   L   !    +-------------------1u3e_M    
                               --3 
  ----------------KG------   L   !                  +-----3qsv_A    
                                 +------------------1 
  ----------------KG------   L                      +-----3kmp_A    
                               

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updated Tue Dec 19 05:22:23 2023