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structure nameH98Q MUTANT OF THE HOMING ENDONUCLEASE I-PPOI COMPLEXED WITH DNA
(Intron-encoded endonuclease I-PpoI)
referenceEastberg et al. Biochemistry 46 7215 2007
sourcePhysarum polycephalum
experimentX-ray (resolution=2.30, R-factor=0.211)
structural superfamilyHis-Me finger endonucleases;
multimeric complexes1a74_AB 1cyq_AB 1cz0_AB 1ipp_AB 2o6m_AB 8vmo_AB 8vmp_AB 8vmq_AB 8vmr_AB 8vms_AB 8vmt_AB 8vmu_AB 8vmv_AB 8vmw_AB 8vmx_AB 8vmy_AB 8vmz_AB 8vn0_AB 8vn1_AB 8vn2_AB 8vn3_AB 8vn4_AB 8vn5_AB 8vn6_AB 8vn7_AB 8vn8_AB 8vn9_AB 8vna_AB 8vnb_AB 8vne_AB 8vnf_AB 8vng_AB 8vnh_AB 8vnj_AB 8vnk_AB 8vnl_AB 8vnm_AB 8vnn_AB 8vno_AB 8vnp_AB 8vnq_AB 8vnr_AB 8vns_AB 8vnt_AB 8vnu_AB
reference complex8vms_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureANRQKTVRLK

Estimated binding specificities ?

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# IC=8.732 IC/col=0.970 n_of_columns=9 specificity:   
A |  90  78   6  78   0  96   0   6   0
C |   0   6   6   6   0   0   0  78  90
G |   6   6  78   6  90   0  96   6   0
T |   0   6   6   6   6   0   0   6   6
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updated Mon Dec 16 19:54:52 2024