1b3t_A : 3D-footprint complex

structure name	EBNA-1 NUCLEAR PROTEIN/DNA COMPLEX (PROTEIN NUCLEAR PROTEIN EBNA1)
reference	Bochkareva et al.
source	Human herpesvirus 4
experiment	X-ray (resolution=2.20, R-factor=0.208)
structural superfamily	Viral DNA-binding domain;
sequence family	Epstein Barr virus nuclear antigen1, DNAbi;
multimeric complexes	1b3t_AB 6pw2_ABCD 6pw2_IKL 7u1t_ABCD 8dlf_ABCD
redundant complexes	6pw2
reference complex	7u1t_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1b3t_A interface=1,4,5,9,15,17,18,54,55,58,59,62, KggWFgkhRgqggsNpKFeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrRgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp
interface signature	KWFRNKFKTYNR

Estimated binding specificities ?

readout + contact

# IC=7.164 IC/col=0.796 n_of_columns=9

specificity:

A |  69  24  19  19   6   0   0   0   0
C |   3  24   5  51   3   0  96  96  88
G |   5  24  69  15   3   0   0   0   5
T |  19  24   3  11  84  96   0   0   3

scan!

Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: EBNA-1
TAGCATATGCTA	PubMed	1b3t_AB(1.85e-11), 6pw2_IJKL(1.59e-09)

Dendrogram of similar interfaces ?

matrix format

  
  WCFT----KG--KGTAYCNGRT--   L                             +5t7x_B    
                                        +------------------1 
  WGFTRTNTKGFTKTTGYCNGRT--   L   +------3                  +1b3t_A    
                                 !      ! 
  --------KG--------------   L --4      +------------------4uzb_B    
                                 ! 
  ----------------KGCGFT--   L   !             +-----------2bop_A    
                                 +-------------2 
  ----------------------RC   L                 +-----------2itl_B

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updated Thu Sep 12 14:32:34 2024