1b3t_A : 3D-footprint complex

structure name	EBNA-1 NUCLEAR PROTEIN/DNA COMPLEX (PROTEIN NUCLEAR PROTEIN EBNA1)
reference	Bochkareva et al.
source	Human herpesvirus 4
experiment	X-ray (resolution=2.20, R-factor=0.208)
structural superfamily	Viral DNA-binding domain;
sequence family	Epstein Barr virus nuclear antigen1, DNAbi;
multimeric complexes	1b3t_AB 6pw2_ABCD 6pw2_IKL 7u1t_ABCD 8dlf_ABCD
redundant complexes	6pw2
reference complex	7u1t_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1b3t_A interface=1,4,5,9,15,17,18,54,55,58,59,62, KggWFgkhRgqggsNpKFeniaeglrallarshverttdegtwvagvfvyggsKTslYNlrRgtalaipqcrltplsrlpfgmapgpgpqpgplresivcyfmvflqthifaevlkdaikdlvmtkpaptcnirvtvcsfddgvdlp
interface signature	KWFRNKFKTYNR

Estimated binding specificities ?

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# IC=6.338 IC/col=0.905 n_of_columns=7

specificity:

A |   7   0   0  96  75   7   9
C |   7   0   0   0   7   7  73
G |  75  96  96   0   7  73   7
T |   7   0   0   0   7   9   7

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Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: EBNA-1
TAGCATATGCTA	PubMed	1b3t_AB(1.85e-11), 6pw2_IJKL(1.59e-09)

Dendrogram of similar interfaces ?

matrix format

  
  WCFT----KG--KGTAYCNGRT--   L                             +5t7x_B    
                                        +------------------1 
  WGFTRTNTKGFTKTTGYCNGRT--   L   +------3                  +1b3t_A    
                                 !      ! 
  --------KG--------------   L --4      +------------------4uzb_B    
                                 ! 
  ----------------KGCGFT--   L   !             +-----------2bop_A    
                                 +-------------2 
  ----------------------RC   L                 +-----------2itl_B

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updated Mon Dec 16 17:39:39 2024