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structure nameSTRUCTURE OF THE FOXM1 DNA BINDING
(Forkhead box protein M1)
referenceLittler et al. 'Nucleic ? ? 2010
sourceHomo sapiens
experimentX-ray (resolution=2.21, R-factor=0.206)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
multimeric complexes3g73_AB 7fj2_AB 7fj2_EF
redundant complexes7fj2_F
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHS

Estimated binding specificities ?

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# IC=5.149 IC/col=0.858 n_of_columns=6 specificity:   
A |   0  87  96  78  19  61
C |   0   0   0   0  61  17
G |   0   9   0   8   8   8
T |  96   0   0  10   8  10
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: FOXM1
TAAACAPubMed3g73_A(5.71e-11), 3g73_AB(2.21e-07)

Dendrogram of similar interfaces ?

matrix format
  
  --------------NAST--RGHT--STLT------   L                      +-------7cby_C    
                                                              +-1 
  --------------NAST--RTHT--ST--------   L             +------2 +-------3l2c_A    
                                                       !      ! 
  ----------STRTSTHG--------------RA--   L         +---3      +---------3zpl_B    
                                                   !   ! 
  RT--LANTHGTTETYTRG------------------   L   +-----4   +----------------1f4k_B    
                                             !     ! 
  --TT------KATTQTTG----LTRT----KAFTYT   L --5     +--------------------2p7c_B    
                                             ! 
  ------------KT--RGAT--RGNT----------   L   +--------------------------8smh_F    
                                           

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updated Fri Sep 13 17:01:44 2024