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structure nameSTRUCTURE OF THE GLYCOSYLASE DOMAIN OF MBD4 BOUND TO AP SITE CONTAINING DNA
(Methyl-CpG-binding domain protein 4)
referenceVigouroux et al. 'Nucleic 40 9917 2012
sourceHomo sapiens
experimentX-ray (resolution=1.79, R-factor=0.216)
structural superfamilyDNA-glycosylase;
redundant complexes4e9g 4e9h 4ea4 4ea5
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  NGRGTG------LG----LCRG------------                               +--------7kz0_A    
                                                              +----5 
  --QG--QG----YC--------------------   L                      !    +--------7ef9_A    
                                                     +--------6 
  ------------YG--------------------                 !        !             +5kn8_A    
                                                     !        +-------------1 
  --QG--RG----YC--------------------             +---7                      +6u7t_A    
                                                 !   ! 
  QGKGLGSGAGSC--LTKC----------------             !   !                     +-4b21_A    
                                                 !   !                   +-2 
  --NG--RG--------FGRC--------------             !   +-------------------3 +-4ejy_A    
                                                 !                       ! 
  --NCNANARC------YGRC--------------          +-10                       +--2xhi_A    
                                              !  !  
  NGRGTG------LG----LC--------------          !  !                    +------6vjw_A    
                                              !  !   +----------------4 
  --QTLAHGAT----------KT------------          !  ! +-8                +------3s6i_A    
                                           +-11  ! ! ! 
  ----------------------RTVAITNAMCRG   L   !  !  +-9 +-----------------------1yrn_A    
                                           !  !    ! 
  --RT--------------------NCSTNARG--   L -12  !    +-------------------------1mnm_C    
                                           !  !  
  ------------------------VAQTNA----   L   !  +-----------------------------1fjl_B    
                                           !  
  ------------------------NT--NAIARG   L   +-----------------------------1b72_B    
                                         

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updated Mon Dec 16 23:09:54 2024