4hqe_A : 3D-footprint complex

structure name	THE CRYSTAL STRUCTURE OF QSRR-DNA COMPLEX (Transcriptional regulator QsrR)
reference	Zhang et al. Proc.Natl.Acad.Sci.USA 110 5010 2013
source	Staphylococcus aureus
experiment	X-ray (resolution=2.30, R-factor=0.208)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	HxlRlike helixturnhelix;
multimeric complexes	4hqe_AB
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4hqe_A interface=37,48,49,50,51,54, mmevcpyleetfkilgrswngliinylsrcndcsahFsdmkrdlktiTPRAlsLklselaqwelvekqiistspvqiiyvltekgkalaealhpieawaqsyvdl
interface signature	FTPRAL

Estimated binding specificities ?

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# IC=4.490 IC/col=0.898 n_of_columns=5

specificity:

A |   0  96  21  42   0
C |   0   0  21  21  96
G |   0   0   0  10   0
T |  96   0  54  23   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ------RGSTRTSTHG------------RA--   L                                   +3zpl_B    
                                             +---------------------------1 
  ----DCLT--AGTTRG----RG------RA--   L       !                           +5h3r_A    
                                           +-4 
  ------------NASTRGHT--STLT------   L     ! !                    +------7cby_C    
                                           ! !       +------------2 
  ------------NASTRTHT--ST--------   L   +-5 +-------3            +------3l2c_A    
                                         ! !         ! 
  TT------KATTQTTG--LTRT----KAFTYT   L   ! !         +-------------------2p7c_B    
                                       --6 ! 
  ------------------YG------------       ! +-----------------------------3eyi_B    
                                         ! 
  --VTSARGTA--RT------------------   L   +-----------------------------6za3_B

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updated Fri Sep 13 18:20:32 2024