interface graph thumbnail
legend  pdf

structure nameX-RAY STRUCTURE OF REB1-TER COMPLEX
(DNA-binding protein reb1)
referenceEscalante et al.
sourceSchizosaccharomyces pombe
experimentX-ray (resolution=2.70, R-factor=0.212)
structural superfamilyHomeodomain-like;
sequence familyMyblike DNAbinding domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRKKYHRRNRDRDRLRY

Estimated binding specificities ?

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# IC=14.692 IC/col=1.049 n_of_columns=14 specificity:   
A |   0   0   4  64   8   0  92   0   0   0   4   4  96   0
C |   4   0  68  12   8   0   0  96  96  96   4   0   0  96
G |   4  96  12  12  12   0   4   0   0   0   4   4   0   0
T |  88   0  12   8  68  96   0   0   0   0  84  88   0   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: REB1
CCGGGTAAPubMed5eyb_B(9.48e-05)
GTCCGGGTAATGCPubMed5eyb_B(4.78e-13)
GCATTACCCGGACPubMed5eyb_B(4.78e-13)
CGGGTAAPubMed5eyb_B(7.92e-06)
GNGCCGGGGTAACNCPubMed5eyb_B(6.44e-03)

Dendrogram of similar interfaces ?

matrix format
  
  ----------------------------KGRTEC--------NAKGNANTST------------------                   +-----------------------------1h89_C    
                                                                                           ! 
  --NARTQT--EC----------------NG--NA------------------------------------   L               !                             +2kdz_A    
                                                                                           !           +-----------------1 
  ----KT--RCEC--NA----------DCNAKANAHTNTSCTC----------------------------   L               !           !                 +1msf_C    
                                                                                         +-7     +-----4 
  ----KG--RAEA--------------DCNAKGNA--NTST------------------------------   L             ! !     !     !    +------------3zqc_A    
                                                                                         ! !     !     +----2 
  ----------------------------------------------------RTRCET----SAQAKT--   L             ! !  +--5          +------------6qec_A    
                                                                                         ! !  !  ! 
  ----KG--RGLC----------------NAKGNA--NTTC------------------------------   L           +-8 !  !  !        +--------------6kks_A    
                                                                                       ! ! +--6  +--------3 
  --------------------RT----STVCKGDC--RG--------------------------------   L           ! !    !           +--------------1w0t_A    
                                                                                       ! !    ! 
  ----------------------HGSGRGHG------RT--------------------------------   L         +-9 !    +--------------------------1tc3_C    
                                                                                     ! ! ! 
  ----------------------------------------------------RARCET----SAQAKG--   L         ! ! +-----------------------------5lxu_A    
                                                                                  +-10 ! 
  ----------------------------------------------------RA------KGSA----KT   L      !  ! +-----------------------------7d3t_D    
                                                                               +-11  !  
  ----------------------------------------------------RTSTVTMCKGDCRGTA--   L   !  !  +-----------------------------1iv6_A    
                                                                             -12  !  
  RT------FTYAQTNAATRG--------------------------------------------------   L   !  +-----------------------------6ryd_F    
                                                                               !  
  --------------------RT------VTKGDC--RGTA------------------------------       +-----------------------------7c4p_A    
                                                                             

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updated Fri Sep 13 19:31:48 2024