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legend  pdf

structure nameCRYSTAL STRUCTURE OF FOXC2 DBD BOUND TO DBE2 DNA
(FORKHEAD BOX PROTEIN C2)
referenceLiang et al. 'Nucleic 47 3752 2019
sourceHOMO SAPIENS
experimentX-ray (resolution=2.40, R-factor=0.230)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
multimeric complexes6o3t_AB
redundant complexes6o3t_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNSRHSL

Estimated binding specificities ?

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# IC=5.185 IC/col=0.864 n_of_columns=6 specificity:   
A |   9  11  19   0   0  96
C |   9   9  11   0   0   0
G |   9  67   9   0   0   0
T |  69   9  57  96  96   0
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Dendrogram of similar interfaces ?

matrix format
  
  --------------NAST--RGHT--STLT--------   L                          +------7cby_C    
                                                                    +-1 
  --------------NAST--RTHT--ST----------   L                +-------2 +------3l2c_A    
                                                            !       ! 
  RT--LANTHGTTETYTRG--------------------   L            +---3       +--------1f4k_B    
                                                        !   ! 
  --------RGSTRTSTHG--------------RA----   L      +-----4   +----------------3zpl_B    
                                                  !     ! 
  --TT------KATTQTTG----LTRT----KA--FTYT   L   +--5     +--------------------2p7c_B    
                                               !  ! 
  ------------KT--RGAT--RGNT------------   L --6  +--------------------------8smh_F    
                                               ! 
  ----------------------YG--------------       +-----------------------------3eyi_B    
                                             

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updated Fri Sep 13 21:17:32 2024