3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameHDAC-PC-NUC
experimentNMR
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes4x23_ABCDEFG 4x23_KLMNOPQ 4xzq_ABCDEFGH 4ys3_ABCDEFGH 6z6p_ABCDEFGHM 6z6p_KN 7ccq_ABCDEFGH 7ccr_ABCDEFGH 7ccr_KV 7ccr_LMNOPQRS 7ea5_ABCDEFGH 7ea8_ABCDEFGH 7ktq_ABCDEFGH 7xd1_ABCDEFGH 8etv_ABCDEF 8eu2_KLMNOP 8eue_ABCDEFHK 8euj_HMOabfhk 8grq_ABCDEFGH 8ieg_CDEFGHKL
redundant complexes8eu2_L 4x23 4xzq 4ys3 7ccq 7ccr 7ea5 7ea8 7ktq 7xd1 8etv 8eue 8euj 8grq 8ieg
links to other resourcesNAKB PDBSum PDIdb DNAproDB 
  
  ----RC                                 +---6qld_f    
                    +--------------------4 
  ----RA            !                    +---7xsx_a    
                    ! 
  LC----       +----6                        +5mlu_A    
               !    !         +--------------2 
  LT----       !    !         !              +4z5t_A    
               !    +---------5 
  LT--RC       !              !                +5xm1_A    
             --7              !              +-1 
  ----RT       !              +--------------3 +8g57_E    
               !                             ! 
  ----RA       !                             +7ea8_A    
               ! 
  --KT--   L   +-----------------------------7cvo_A

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updated Tue Dec 19 16:35:46 2023