3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameHDAC-PC-NUC
experimentNMR
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes4x23_ABCDEFG 4x23_KLMNOPQ 4xzq_ABCDEFGH 4ys3_ABCDEFGH 6z6p_ABCDEFGHM 6z6p_KN 7ccq_ABCDEFGH 7ccr_ABCDEFGH 7ccr_KV 7ccr_LMNOPQRS 7ea5_ABCDEFGH 7ea8_ABCDEFGH 7ktq_ABCDEFGH 7xd1_ABCDEFGH 8grq_ABCDEFGH 8ieg_CDEFGHKL 8wg5_ABCDEFGH
redundant complexes4x23 4xzq 4ys3 7ccq 7ccr 7ea5 7ea8 7ktq 7xd1 8grq 8ieg 8wg5
links to other resourcesNAKB PDBSum PDIdb DNAproDB 
  
  --RT----                                   +8u14_G    
                                           +-1 
  --RA----                       +---------4 +1zla_C    
                                 !         ! 
  --RG----                  +----5         +5x0y_G    
                            !    ! 
  --RA--RA             +----6    +---------6a5l_g    
                       !    ! 
  --RG----             !    !              +8txv_G    
                     +-8    +--------------2 
  --RG----           ! !                   +8ox0_C    
                 +---9 ! 
  ----RA--       !   ! +-------------------6g0l_D    
                 !   ! 
  --RG----       !   +--------------------8jla_C    
               -10  
  --RA----       !                        +8rbx_M    
                 !         +--------------3 
  --RT----       +---------7              +8grq_A    
                           ! 
  LCRT----                 +--------------8hr1_E

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updated Wed Dec 18 07:11:29 2024