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structure nameCRYSTAL STRUCTURE OF C/EBPBETA BZIP HOMODIMER BOUND TO A HIGH AFFINITY DNA FRAGMENT
(CAATENHANCER BINDING PROTEIN BETA)
referenceTahirov et al.
sourceHOMO SAPIENS
experimentX-ray (resolution=1.80, R-factor=0.232)
structural superfamilyLeucine zipper domain;
sequence familyBasic region leucine zipper; bZIP transcription factor;
multimeric complexes1gtw_AB 1gu4_AB 1gu5_AB 1h88_ABC 1h8a_ABC 1io4_ABC 2e42_AB 2e43_AB 7upz_AB
redundant complexes1gtw_A 1gu5_A 1h8a_B 1io4_A 2e42_B 2e43_B 7upz_A 1h88
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNNAVSR

Estimated binding specificities ?

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# IC=4.628 IC/col=0.926 n_of_columns=5 specificity:   
A |  54   0   0   0  16
C |  29   0   0   0  54
G |   0   0   0  96  13
T |  13  96  96   0  13
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: EBPBETA
CCAATPubMed1gu4_B(1.98e-04)
TTGC|GTCAPubMed1gu4_B(3.92e-03), 1h88_A(5.94e-03), 2e42_B(3.44e-03), ... (total=4)
TGAC|GCAAPubMed1gu4_B(3.92e-03), 1h88_A(5.94e-03), 2e42_B(3.44e-03), ... (total=4)

Dendrogram of similar interfaces ?

matrix format

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updated Thu Dec 22 17:33:34 2022