interface graph thumbnail
legend  pdf

structure nameSTRUCTURAL BASIS FOR CELL TYPE SPECIFIC DNA BINDING OF C/EBPBETA: THE CASE OF CELL CYCLE INHIBITOR P15INK4B PROMOTER
(CCAATenhancer-binding protein beta)
referenceLountos et al. J.Struct.Biol. 214 107918 2022
sourceHomo sapiens
experimentX-ray (resolution=2.49, R-factor=0.215)
structural superfamilyLeucine zipper domain;
sequence familyBasic region leucine zipper; bZIP transcription factor;
multimeric complexes1gtw_AB 1gu4_AB 1gu5_AB 1h88_ABC 1h89_ABC 1h8a_ABC 1hjb_ABC 1hjb_DEF 1io4_ABC 2e42_AB 2e43_AB 6mg1_AB 6mg2_AB 6mg3_AB 7l4v_AB 7upz_AB
reference complex6mg1_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNNAVSR

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5 specificity:   
A |   0   0  13   0  16
C |   0   0  13  96  13
G |   0   0  16   0  13
T |  96  96  54   0  54
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updated Fri Sep 13 08:08:10 2024