interface graph thumbnail
legend  pdf

structure nameSTRUCTURAL BASIS FOR CELL TYPE SPECIFIC DNA BINDING OF C/EBPBETA: THE CASE OF CELL CYCLE INHIBITOR P15INK4B PROMOTER
(CCAATenhancer-binding protein beta)
referenceLountos et al. J.Struct.Biol. 214 107918 2022
sourceHomo sapiens
experimentX-ray (resolution=2.49, R-factor=0.215)
structural superfamilyLeucine zipper domain;
sequence familyBasic region leucine zipper; bZIP transcription factor;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNNAVSR

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5 specificity:   
A |  54   0  57  96  96
C |  13   0  13   0   0
G |  13  96  13   0   0
T |  16   0  13   0   0
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updated Tue Dec 17 13:41:44 2024