1k61_B : 3D-footprint complex

structure name	MATALPHA2 HOMEODOMAIN BOUND TO DNA
reference	Wolberger et al. 'NUCLEIC 30 5244 2002
experiment	X-ray (resolution=2.10, R-factor=0.221)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
multimeric complexes	1akh_AB 1apl_CD 1k61_ABCD 1le8_AB 1mnm_ABCD 1yrn_AB
redundant complexes	1apl_D 1akh 1le8 1mnm 1yrn
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1k61_B interface=3,4,47,50,51,54, rgHRftkenvrileswfaknienpyldtkglenlmkntslsriqikNwvSNrrRkekti
interface signature	HRNSNR

Estimated binding specificities ?

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# IC=8.773 IC/col=0.627 n_of_columns=14

specificity:

A |   0   0   0  89   6   6   6  24  24  24  24  24  20   0
C |   0   0   0   1   6   6   0  24  24  24  24  24   6  96
G |   0  96   0   6  71  16   1  24  24  24  24  24  57   0
T |  96   0  96   0  13  68  89  24  24  24  24  24  13   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  RT------------NT--NAIARG   L           +-----------------------------1b72_B    
                                       +-1 
  --RT----------NT--NAIARG   L       +-2 +-----------------------------4cyc_B    
                                     ! ! 
  RA------------IAQTNA----   L     +-3 +-----------------------------5ego_B    
                                   ! ! 
  RT------------VTQTNA--RG   L   +-4 +-----------------------------8ejp_B    
                                 ! ! 
  ----------STTAQCST------     --5 +-----------------------------8b4b_W    
                                 ! 
  ----STRGQTQAST----------   L   +-----------------------------7t8k_B

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updated Sat Jan 10 04:44:09 2026