interface graph thumbnail
legend  pdf

structure nameMATALPHA2 HOMEODOMAIN BOUND TO DNA
referenceWolberger et al. 'NUCLEIC 30 5244 2002
experimentX-ray (resolution=2.10, R-factor=0.221)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes1k61_ABCD
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureHRNSNR

Estimated binding specificities ?

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# IC=8.732 IC/col=0.624 n_of_columns=14 specificity:   
A |   0   0   0  89  14   6   6  24  24  24  24  24  51   0
C |   0   0   0   0   6   0   8  24  24  24  24  24   8  96
G |   0  96   0   7  64   1   6  24  24  24  24  24  25   0
T |  96   0  96   0  12  89  76  24  24  24  24  24  12   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RT------ITQCNAMC--   L     +-----------------------------2r5y_A    
                           +-2 
  --------VA--NAQART   L   ! !                           +-1o4x_A    
                         --3 +---------------------------1 
  --------VTCCNAQART   L   !                             +-8g87_X    
                           ! 
  --RTRGTTKT--------   L   +-----------------------------2o8k_A    
                         

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updated Sun Aug 3 05:41:02 2025