1k61_B : 3D-footprint complex

structure name	MATALPHA2 HOMEODOMAIN BOUND TO DNA
reference	Wolberger et al. 'NUCLEIC 30 5244 2002
experiment	X-ray (resolution=2.10, R-factor=0.221)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
multimeric complexes	1akh_AB 1apl_CD 1k61_ABCD 1le8_AB 1mnm_ABCD 1yrn_AB
redundant complexes	1apl_D 1akh 1le8 1mnm 1yrn
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1k61_B interface=3,4,47,50,51,54, rgHRftkenvrileswfaknienpyldtkglenlmkntslsriqikNwvSNrrRkekti
interface signature	HRNSNR

Estimated binding specificities ?

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# IC=8.684 IC/col=0.620 n_of_columns=14

specificity:

A |   0   0   0  91  10   5   5  24  24  24  24  24  21   0
C |   0   0   0   0   7   5   5  24  24  24  24  24   5  96
G |   0  96   0   5  69  10   5  24  24  24  24  24  58   0
T |  96   0  96   0  10  76  81  24  24  24  24  24  12   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --RT----------NT--NAIARG   L                           +4cyc_B    
                                        +----------------1 
  --------------NCITNARGRG   L     +----2                +6fqq_E    
                                   !    ! 
  RT------------VTQTNA--RG   L   +-3    +----------------8ejp_B    
                                 ! ! 
  ----------STTAQCST------     --4 +---------------------8b4b_W    
                                 ! 
  ----STRGQTQAST----------   L   +-----------------------7t8k_B

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updated Mon Jun 29 14:21:09 2026